Grading and frequency of pulmonary hypertension in chronic obstructive pulmonary disease patients
Journal Title: Medpulse International Journal of Medicine - Year 2018, Vol 5, Issue 1
Abstract
Background: India is a developing country, and due to industrialization, the incidence of COPD has been increasing day by day. Pulmonary hypertension (PH) is most common complication of Chronic Obstructive Pulmonary Disease (COPD). Those who are exposed to long term biomass smoke and tobacco smoke develop COPD. Aims and Objective: To detect Frequency and Grading of PH in COPD patients. Material and methods: COPD patients are diagnosed with the help of pulmonary function test (PFT) and duration of exposure to biomass or tobacco smoke. PH is detected with the help of 2D ECHO. Other causes of PH are excluded. Observation: Frequency of PH is more common in female (53.4%) than male (46.6%). Out of 60 patients 36.7 % developed mild, 36.6% developed moderate and 26.7 % developed severe PH. Frequency of PH in moderate COPD is 58.3%, Severe COPD is 33.3% and very severe COPD is 3.3%. Conclusion: There is increased incidence of PH in COPD due to Biomass smoke (53.4%) as compared to Tobacco smoke (46.6%). PH in COPD has female preponderance. COPD is more commonly associated with mild to moderate PH. Severe PH is associated with advanced disease and poor outcome. Endothelial dysfunction, Inflammation, Hyperinflation and Chronic hypoxia are affiliated with PH in COPD patients.
Authors and Affiliations
Mahesh Deshmukh, Pankaj Palange, Harshal Patil, Abhijeet Nashte, Satyajeet Borade, Mohit Singhal
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