Clinical Evaluation of Medadusti in Pre-Diabetic Stage and Its Management with Trikatu Churna
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2017, Vol 2, Issue 4
Abstract
In human body, digestion, absorption and metabolism depend on the function of Jatharagni, Bhutagni and Dhatwagni. Meda Dhatu is produced from Mamsa Dhatu with the help of Mamsagni. Due to vitiation of Meda Dhatu several diseases have been produced, among them Prameha i.e. diabetes mellitus is an important disease. The causative factor of Medavaha Srota Dusti and Prameha are identical. Similarly, the features of Medadusti and the features of Purvarupa of Prameha are identical. Meda is the chief Dushya of Prameha. Meda can be compared with body fat and multiple forms of lipids like cholesterol, triglycerides, low density lipoproteins (LDL), very low density lipoproteins (VLDL) etc. Alteration of fat metabolism in the pathogenesis of diabetes mellitus is an important phenomenon. In the present study, the conceptual understanding of Medadusti in Prameha (mainly in its prodromal stage) has been clinically verified in 32 subjects having prodromal features of Prameha i.e. having pre-diabetic stage. The Medadusti Lakshans in terms of Medavriddhi Lakshans have been considered as subjective parameters whereas the blood level of total cholesterol, triglyceride and fating & post prandial blood glucose has been taken as objective parameters. Most of the subjects have satisfied the subjective criteria of Medadusti in prodromal stage of Prameha, which validates the conceptual understanding of Medadusti being an essential pathological phenomenon in occurrence of Prameha. The efficacy of the stipulated drug i.e. Trikatu Churna has been verified through subjective and objective parameters and statistically analyzed using paired âtâ test before and after treatment. Statistical analysis before and after administration of Trikatu Churna for two month in stipulated dose shows the âpâ value <0.001 in most of the parameters (subjective and objective). This indicates the drug taken for the study is highly efficacious against Medadusti and subsequently helps to combat the occurrence of Prameha i.e. diabetes mellitus.
Authors and Affiliations
Sukalyan Ray
Keywords
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