CLINICAL FEATURES OF RDS COURSE DEPENDING ON ANTE AND POSTNATAL PREVENTIVE ADMINISTRATION OF SURFACTANT
Journal Title: International scientific journal Science and Innovation - Year 2024, Vol 3, Issue 9
Abstract
The most common cause of death in premature infants is respiratory distress syndrome. The aim of this study is to evaluate the effectiveness of antenatal corticosteroid prophylaxis in combination with early surfactant administration to newborns on the course and outcomes of respiratory distress syndrome. The cohort study included 80 premature infants with gestation periods from 27 to 34 weeks. A comparative assessment of the effectiveness of antenatal corticosteroid prophylaxis and early therapy with curosurf in the delivery room on the course and outcomes of RDS was carried out. Antenatal corticosteroid prophylaxis in combination with early surfactant therapy with curosurf at a dose of 200 mg / kg in the delivery room contribute to a more rapid normalization of the gas exchange function of the lungs in premature infants with respiratory distress syndrome; reduce the frequency of intraventricular hemorrhages; reduce the duration of respiratory support of the newborn and the need for mechanical ventilation by 2 times; reduce the length of stay in the intensive care unit and hospital by 2 times.
Authors and Affiliations
Ismailova M. A. , Khodjamova N. K.
Keywords
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- EP ID EP748019
- DOI 10.5281/zenodo.13834869
- Views 49
- Downloads 0
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