Clinical Importance of Evaluation of Iron Profile Parameters in Hypothyroid Patients
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 1
Abstract
Introduction: The prevalence of iron deficiency anaemia has been found to further increase along with increase in the incidence of thyroid disorders. Low thyroid function has been one of the most overlooked causes of iron deficiency anaemia. Also, normal thyroid status requires adequate levels of many trace elements, which include iodine and iron. This study was carried out for estimation of the levels of serum iron, TIBC and serum ferritin in hypothyroid patients. Methods: This case-control study was carried out at a tertiary care center. 100 cases of hypothyroidism and 100 apparently healthy euthyroid controls were enrolled for the study. Apart from routine laboratory investigations, measurement of serum ferritin, iron and TIBC was done. Diagnosis of hypothyroidism was confirmed by measurement of levels of free T3, free T4 and TSH. Results: Patients of hypothyroidism had significantly lower levels of iron and ferritin, while TIBC was significantly higher in these patients in comparison with euthyroid healthy controls. (p = 0.00, p =0.00, p = 0.00). Strong positive correlation was established between the levels of free T4 and serum ferritin (r = + 0.63, p< 0.05) in these patients. Conclusion: Hypothyroidism may cause bone marrow repression and/or decrease in production of erythropoietin. In our case-control study, a large number of hypothyroid patients had underlying iron deficiency anaemia as well. So screening for iron deficiency anaemia and its timely treatment should be regarded as an important part of treatment in hypothyroid patients to achieve best results.
Authors and Affiliations
Neeraj Singla, Heena Singla
Keywords
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- EP ID EP529114
- DOI 10.21276/ijmrp.2018.4.1.017
- Views 114
- Downloads 0
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