Clinical Outcome of High Risk Gastrointestinal Stromal Tumor in a Meckel’s Diverticulum

Journal Title: International Journal of Biomedical Science (IJBS) - Year 2009, Vol 5, Issue 1

Abstract

We describe a seven years follow-up of a high risk gastrointestinal stromal tumor in a Meckel’s diverticulum in a 68-year-old man with abdominal pain and vomiting. The patient was operated in emergency for peritonitis due to perforation of small intestine and treated with imatinib mesylate. The metastatic progression of the disease demonstrated the value of prognostic indicators (mitotic rate >10/50 high power field, necrosis and 8 cm in maximum diameter) for assessing risk of aggressive behaviour. Computed tomography was a valuable procedure for detection of local recurrence, the distant metastases and for surveillance after surgery in the follow-up. The review of the literature shows that this case has the longest follow up and consents the comparisons of the same neoplasm in other sites most frequent and better described than Meckel’s diverticulum.

Authors and Affiliations

Michele Scialpi, Luciano Lupattelli, Christian Franzini, Antonio Cavaliere, Francesco Barberini, Irene Piscioli, Ilaria Franceschetti

Keywords

Related Articles

Spectrophotometric Determination of Risedronate in Pharmaceutical Formulations via Complex Formation with Cu (II) Ions: Application to Content Uniformity Testing

A simple, sensitive, rapid and accurate spectrophotometric method was developed for the determination of risedronate, a bisphosphonate drug important for the treatment of a variety of bone diseases, in raw material and p...

Transforming Growth Factor-β1 and Laminin-111 Cooperate in the Regulation of Expression of Interleukin-6 and Interleukin-8 in Synovial Fibroblasts

In a recent study we showed that binding of synovial fibroblasts (SF) to laminin-111 (LM-111) in the presence of TGF-β1 induced a significant production of IL-16. Here we go on to investigate the regulation of IL-6 and I...

Use of Gelatinized Maca (Lepidium peruvianum) in Early Postmenopausal Women - a Pilot Study

Objective: This double-blind, placebo-corrected clinical pilot study was aimed at assessing the use of hypocotyls of cruciferous Andean plant Maca (Lepidium peruvianum Chacon), in alleviating symptoms of menopausal disco...

Characterization of Molecular Evolution in Multi-Drug Resistant of Mycobacterium tuberculosis by rpoB Gene in Patient with Active Pulmonary Tuberculosis from Iranian Isolates

This is the first genetic biodiversity study of Mycobacterium tuberculosis in Iran. Thus, we investigated the genetic patterns of strains isolated in the first survey of anti-tuberculosis drug-resistance by rpoB gene as...

Lower-Dose and Long-Term Intermittent Interferon Therapy for Hepatitis C Genotype 2a may be a Possibility

We report two recent, successful cases in treating active chronic hepatitis C patients (genotype 2a) with a lower-dose and long-term intermittent interferon therapy. Case 1: A 67-year-old female received IFN-alpha 3 MU t...

Download PDF file
  • EP ID EP84490
  • DOI -
  • Views 111
  • Downloads 0

How To Cite

Michele Scialpi, Luciano Lupattelli, Christian Franzini, Antonio Cavaliere, Francesco Barberini, Irene Piscioli, Ilaria Franceschetti (2009). Clinical Outcome of High Risk Gastrointestinal Stromal Tumor in a Meckel’s Diverticulum. International Journal of Biomedical Science (IJBS), 5(1), 74-78. https://europub.co.uk/articles/-A-84490