Evaluation of Ginkgo Biloba Extract on Hematological Changes Affected with Hazards of Electromagnetic Field Exposure
Journal Title: International Journal of Biomedical Science (IJBS) - Year 2009, Vol 5, Issue 3
Abstract
The aim of the present work is to study if the GBE 761 (Ginkgo biloba leaves extract) which is beneficial in arterial disease owing to its vasodilator and blood flow acts against the hazards of exposure to electromagnetic field. Here, the GBE was used in two ways either as a protector or for treating the hazards due to exposure to electromagnetic field (EMF). For this purpose, albino rats were grouped into six groups and blood samples were collected from eye vein of the animals from all groups at the end of the experiment. This study concentrates on the cellular membrane and function of the RBCs and focuses on the rheological and physical measurements for blood and hemoglobin molecule because the RBCs membranes play an essential role in the blood flow rate. The changes in its biophysical properties of RBCs membrane will affect its capability for carrying on its metabolic functions. Furthermore, the molecular diameter of hemoglobin, its relaxation time and conductivity were calculated from the dielectric relaxation data. The results indicate that the administration of GBE led to the decrease of RBCs membrane elasticity will lead to the increase of the blood viscosity. Results suggest that GBE may be not of clinical value as anti-oxidant drug for such diseases occurred due to to EMF exposure for long time. It may be conclude that through treatment with those extract some physical measurements like "viscosity of blood, Osmotic fragility to measure the hemolysis rat of RBCs, the radius and the conductivity of hemoglobin molecule" should be considered during the time of treatment. Overall, these leaves (GBE) need more study and there is a recommendation to put the physical parameters parallel to the clinical study.
Authors and Affiliations
H. E. Abdel Baieth
Keywords
Related Articles
- EP ID EP84534
- DOI -
- Views 110
- Downloads 0
Spectrophotometric Determination of Risedronate in Pharmaceutical Formulations via Complex Formation with Cu (II) Ions: Application to Content Uniformity Testing
A simple, sensitive, rapid and accurate spectrophotometric method was developed for the determination of risedronate, a bisphosphonate drug important for the treatment of a variety of bone diseases, in raw material and p...
Spectrophotometric Determination of Pipazethate HCl and Dextromethorphan HBr using Potassium Permanganate
Rapid, simple and sensitive validated spectrophotometric methods have been described for the assay of pipazethate HCl (PiCl) and dextromethorphan HBr (DEX) either in pure form or in pharmaceutical formulations. The propo...
<br /> Dietary Supplementation of Vitamin E and α-lipoic Acid Upregulates Cell Growth and Signaling Genes in Rat Myocardium
The efficacy of antioxidant supplementation in the prevention of cardiovascular disease appears equivocal, however the use of more potent antioxidant combinations than those traditionally used may exert a more positive e...
HIV/AIDS Knowledge, Attitudes, and Behaviors of Construction Workers in China
The objective of the study was to describe HIV/AIDS knowledge, attitudes, risk behaviors, and sources of information among construction workers in China. A cross-sectional survey of 458 construction workers was conducted...
Pseudomonas Aeruginosa Endocarditis in Acute Myeloid Leukemia. A Rare Complication
Infectious endocarditis is a rarely encountered complication among leukemia patient during induction therapy. We describe a young patient who developed prolonged high fever after aggressive chemotherapy for Acute Myeloid...