Clinical Outcomes in Patients with Diabetes Mellitus Using a Medically Supervised Commercial Weight Reduction Program Compared to Standard Care in an Endocrine Specialty Clinic
Journal Title: Journal of Diabetes and Obesity - Year 2016, Vol 3, Issue 2
Abstract
Aims: To evaluate metabolic and anthropometric changes achieved and maintained by diabetic patients (pts) in a structured weight loss (WL) program vs usual care in an endocrine clinic (UCG). Materials and Methods: This retrospective comparison study examined 38 diabetic pts with BMI >25 undergoing the active weight loss phase of WL determined by patient goal weight and then followed for 6 months in weight maintenance phase (WM). Multiple endpoints were assessed at baseline including BMI and hemoglobin A1c (A1c). Endpoints were reassessed at 6 months in WM. The usual care group (UCG) was obtained through chart review of 26 diabetic pts with BMI > 25 in an endocrine specialty clinic who completed an education program including lifestyle counseling by a certified diabetic educator. Data were analyzed using ANCOVA and protected LSD, adjusting for age, gender, and baseline weight. Results: Patients showed a change in BMI at 6 months of -6.8 ± 0 (bsl 44 ± 8.4) and -0.7 ± 1.1 (bsl 35 ± 6.2) for HMR® pts and UCG, respectively (p < 0.05). HMR® pts had 13.4% ± 3 % WL vs 7.9% ± 4% in UCG p = 0.34). 6 month A1c was similar in HMR pts (7.5% ± 2; bsl 8.3 ± 1.9) and UCG (7.5% ± 2.3; bsl 9.8 ± 1.8). HMR® pts had a reduction of total medication usage of 28%, with at least one medication discontinued in 80% of pts, while the UCG had only 23% of pts with discontinuation of at least one medication (p < 0.05). Conclusions: Compared to CDE-led diabetic education emphasizing lifestyle change, pts in an intensive WL program utilizing weekly coaching, meal replacements, and exercise, had a significant decrease in BMI and achieved a similar A1c with reduction in medication requirements.
Authors and Affiliations
Ryan Kennedy
Keywords
Related Articles
- EP ID EP417844
- DOI 10.15436/2376-0494.16.839
- Views 101
- Downloads 0
Protective effects of Macrotyloma uniflorum seeds (horse gram) in abnormalities associated with the metabolic syndrome in rats
Macrotyloma uniflorum Lam Verdc known as horse gram is an underutilized - unexplored legume distributed throughout Asia - Africa Its seeds are rich in antioxidant phenolic acids ferulic acid being the most potent o...
Diabetes Risk Factors for Chronic Kidney Patients
Diabetes Mellitus DM Chronic Kidney Disease CKD and Coronary Heart Disease CHD are in practice a complex medical status which are closely associated and generally coexist This article focuses the diabetes risk f...
Alstrom Syndrome with a Mutation in Exon8 (C.4746C > A) of Alstrom Syndrome Protein 1 Gene: The First Case Report and Literature Review
Alström syndrome (AS) is a rare, autosomal recessive disorder characterized by progressive cone-rod dystrophy, childhood obesity, sensorineural hearing impairment, type 2 diabetes, hypogonadism, and additional abnormalit...
Comparative Efficiency of Sulfonylurea and/or Dipeptidyl Peptidase-4 inhibitor in Basal-Supported Oral Therapy in Japanese Patients with Type 2 Diabetes (JDDM39)
Basal-supported Oral Therapy BOT comprising treatment with oral antidiabetic drugs and once-daily injections of a long-acting insulin analog is a convenient regimen However it sometimes fails to achieve satisfactor...
Association of Sedentary Behaviour and Mental Health among Young Adults: A Cross-Sectional Study
emsp emsp Sedentary behaviour contributes to adverse physical health outcomes in youth Although evidence for the relationship between sedentary behaviour and mental health outcomes is emerging little is known regar...