Clinical Pharmacist’s Interventions In Adverse Drug Reactions
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 5
Abstract
Adverse drug reactions (ADRs) are broadly divided into predictable (related to pharmacologic actions of the drug in otherwise normal individuals) and unpredictable reactions (related to individual’s immunological response and, on occasion, to genetic differences in susceptible patients). Drug allergy is a type of unpredictable reaction. "Drug allergy" refers to immunologically mediated drug hypersensitivity reactions. These may be either immunoglobulin E (IgE)–mediated (immediate) or non–IgE-mediated (delayed) hypersensitivity reactions. The involvement of a critical care pharmacist has been shown to prevent ADE, and reduce the morbidity and today they are recognized as an integral member of critical care team along with the other health care professionals. The idea of a specialized intensive care pharmacist was first established in the world of pharmacy in 1982. I report a series of three case reports to display the interventions of clinical pharmacist in the management and further prevention of the drug reactions. Penicillin induced acute urticaria, Cefexime induced Steven Johnson Syndrome and Valproate induced Rise in Liver enzymes are three cases of drug reactions and the interventions of Clinical Pharmacist in the management and prevention of further recurrence has been reported in the present article.
Authors and Affiliations
Sukesh Krishna Chaitanya Loka
Keywords
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