“Clinical Profile and Histopathological Pattern of Cervical Lymphadenopathy: A Study in Dhaka Medical College Hospital, Dhaka, Bangladesh”
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
A total of 115 consecutive patients having cervical lymphadenopathy both inpatient and outpatient department in the above mentioned hospitals were enrolled in this study to see the clinicopathological correlation. Almost one third (29.6%) patients belonged to age 21-30 years and the mean age was found 42.1±15.6 years. The association between age with histological findings it was observed that lymphoma was found 27.6% in patients belonged to age 41-50 years, tuberculosis 14(43.8%) patients belonged to age 21-30 years, metastatic carcinoma was 10(41.7%) patients belonged to age 51-60 years, nonspecific lymphadenopathy 11(45.8%) patients belonged to age 21-30 years. Male to female ratio was 2.59:1. More than three fourth patients were married. More than one fourth, patients were laborer, one third were businessman, and others were housewives, student, and unemployed. More than half of the patients came from lower class and others from middle class family. Regarding the clinical feature of the study patients, it was observed that majority patients had nonspecific symptom like generalized weakness, loss of appetite and weight loss, other features like fever, cough and headache also present in less number. Examination cervical lymph node observed that most of the lymph node was non tender, discreet in character, firm in consistency and mobile. On the other hand lymph nodes fixed in metastatic carcinoma and matted in tuberculosis. On systemic examination, it was observed that splenomegaly and hepatomegaly were the common finding followed by ascites. Organomegaly was frequently seen lymphoma while ascites in metastatic cases.More than three fourth of the patients had normal findings in CXR P/A view followed by features of consolidation, features of effusion, bilateral hilar shadow and features of fibrosis. Hemoglobin level showed most patients were anaemic. Erythrocyte sedimentation rate were also high in most of the patients. Total count of WBC of the study patients were within normal limit. FNAC of lymph node was done in 45 cases and among them tuberculosis was found 21(46.7%), lymphoma 8(17.8%), metastatic carcinoma 8(17.8%), nonspecific lymphadenopathy 6(13.3%) and others were 2(4.4%). Biopsy of lymph node was done in 70 cases among them 21(30.0%) patients had lymphoma, 18(25.7%) had nonspecific lymphadenopathy, 16(22.9%) had metastatic carcinoma, 11(15.7%) had tuberculosis. Diagnosis of study patients by histopathology and other relevant investigations finally observed that 34(29.6%) patients had tuberculosis, 29(25.2%) had lymphoma, 24(20.9%) had metastatic carcinoma, 14(12.2%) had nonspecific lymphadenopathy. Other less common diagnosis were Systemic lupus erythematosus, Kikuchi’s diseases, Sarcoidosis, Sinus histocytosis, Inflammatory lesion and Papillary carcinoma of Thyroid.
Authors and Affiliations
Dr. Shaha Md. Ashrafozzaman, Dr. Md. Robed Amin, Dr. Md. Jahirul Haque
Keywords
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- EP ID EP452701
- DOI 10.9790/0853-1801196572.
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