CLINICAL PROFILE AND MANAGEMENT OF LIVER ABSCESS (AMOEBIC AND NON-AMOEBIC) AND COMPARISON BETWEEN CONSERVATIVE MANAGEMENT AND PIGTAIL CATHETERISATION IN NORTH-CENTRAL INDIA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 95
Abstract
BACKGROUND Liver abscess is a common and major health problem in the lower socio-economic group. It can be managed with drugs, ultrasoundguided needle aspiration and open surgical drainage. The aim of the study was to assess the variation in clinical presentation in liver abscesses and to study the therapeutic efficacy of conservative management and ultrasound-guided pigtail drainage of liver abscess and to compare the two modalities of treatment of liver abscess. MATERIALS AND METHODS The study was conducted in the GSVM Medical College and Associated LLR Hospital Kanpur and Rama Medical College Kanpur from December 2010 to October 2014 among 224 patients (Case Group), out of which 100 cases (study group) were selected for comparing the two modalities of treatment of uncomplicated LA (Liver Abscess). Study by convenient allocation since the duration of the study was few months. The patients were selected by convenience allocation technique. The sample size estimation was also done at conveniences. The treatment modalities to be compared included conservative management versus ultrasound-guided pigtail drainage of LA measuring between 6.0 and 10.0 cm in the maximum diameter. RESULTS In the study group, there was history of alcohol intake in 63/100 cases (63%) and most of the patients belonged to the lower socioeconomic status and of these 49% were unskilled labourers. The mean value of serum bilirubin in Group 1 was 0.92 ± 0.14 mg/dL, whereas in Group 2 was 0.95 ± 0.14 mg/dL. The mean value of serum ALP in study Group 1 was 310 ± 67.49 IU/L and in Group 2 was 373.5 ± 88.29 IU/L. CONCLUSION Liver abscess, a dreadful disease of a time can be very well managed these days if uncomplicated. Either by conservative therapy or an ultrasonographically guided pigtail catheterisation with better result and quicker healing rates, quicker reduction in TLC count, faster improvement in symptoms {decrease in VAS (visual analogue score)} with USG-guided method, although a longer stay in the hospital but overall a better option than conservative management for larger abscess cavities.
Authors and Affiliations
Yadav G. D, Kuldeep Kumar, Anju Yadav, Vinod Kumar, Deepak Lohia, Mukesh Bisht, Rupesh Kunj Bihari, Arvind Sharma
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