Clinical profile of brucellosis - A cross sectional study
Journal Title: MedPulse -International Medical Journal - Year 2017, Vol 4, Issue 4
Abstract
Background and Objectives: Human brucellosis is an important but neglected disease in India. It is traditionally described as a disease of protean manifestations. The aim of this study was to access the epidemiological, clinical and laboratory characteristics of brucellosis. Methods: In this cross sectional study, all the patients admitted with symptoms and signs suggestive of brucellosis were screened serologically for brucellosis by standard agglutination test. A total of 30 cases diagnosed as brucellosis were investigated in terms of spread of infection, age and sex distribution, clinical and laboratory characteristics and response to different treatment regimens. Result: Our study revealed a prevalence of 0.61 percent in adults and 0.1 percent in children. Fever with drenching sweats remained one of the most important symptoms of brucellosis. Other common symptoms were generalized weakness, anorexia, bodyache, joint pain and headache. Amongst the signs, hepatomegaly and splenomegaly were more common wheras lyphadenopathy was seen in only few cases. All patients responded to either of the drug regimens, namely rifampicin plus doxycycline or rifampicin plus streptomycin. Overall prognosis was good and none of the patients expired. Conclusion and Interpretation: It is concluded that brucellosis is a disease with protean manifestation with no single diagnostic symptom or sign. Brucellosis should be considered as a differential diagnosis in all cases of pyrexia of unknown origin, low backache, arthralgia, sciatica and in all cases of progressive weight loss
Authors and Affiliations
Swapnil Ganeshpure, Sham Kamble
Keywords
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