Clinical Profile of Dengue in a Tertiary Care Hospital of Rohelkhand of U.P.(Bareilly)

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Clinical Profile of Dengue in a Tertiary Care Hospital of Rohelkhand of U.P.(Bareilly)

Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 4

Abstract

Dengue fever has emerged as one of the major health problems in North India in recent years. The 2011 epidemic and beyond had created concern about the efforts regarding the prevention and treatment of this disease at the country level. This study will highlight different clinical and laboratory features in patients with dengue fever in a tertiary care hospital which will go a long way in guiding primary care clinicians in diagnosing and managing such patients. Material and methods- Seventy-two cases of dengue positive for dengue IgM and antibodies (ELISA) were included in this study. All relevant parameters were studied and analyzed with the help of STAT-A software version 2.0. The severity was classified as per WHO guidelines. They were submitted to detailed clinical history and laboratory investigation for hematocrit values, liver and renal function test. Observations- Seventy-two cases of dengue were taken for this study of age varied from 8 to 69 years with mean ± SD= 32.6 ± 8.6 years and male to female ratio of 1.5:1. The most affected age group was 20 to 39 years (61.1%). Most of the cases were of dengue hemorrhagic fever (DHF=61.1%), Dengue fever(DF=35%) and dengue shock syndrome(DSS=4.17%). Common manifestations were fever, diminished/loss of appetite, headache, body ache in all patients. Bleeding manifestations (52.8%) were seen in the form of petechial rashes (52.8%), hematemesis (2.8%), malena (13.9%), conjunctival hemorrhag e (13.9%) with platelets< 50,000/cumm. Liver involvement was with hyperbilirubinemia and more than two fold increase of serum transaminases. Overall mortality was 8.4% with two cases out of 3 cases of Dengue Shock Syndrome. Recovery was fast with Dengue fever cases as compared to others. Conclusion- The appropriate investigation, strict monitoring and prompt supportive management can reduce the mortality. This study indicates that dengue hemorrhagic fever is a common manifestation and dengue should be considered as a differential diagnosis in patients with clinical bleeding manifestation in association with raised liver enzymes.

Authors and Affiliations

Amit Sachan

Keywords

Dengue fever (DF) Dengue hemorrhagic fever(DHF) and Dengue Shock(DSS) Dengue rashes and Bleeding

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EP ID EP211300
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