Clinical Profile of Tuberculosis in HIV Patients Attending the ART Centre in a Tertiary Care Hospital in North India
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 1
Abstract
HIV/AIDS pandemic is responsible for the resurgence of TB worldwide. HIV and Mycobacterium tuberculosis have a synergistic interaction. Coinfection with HIV infection leads to difficulties in both the diagnosis and treatment of tuberculosis, increase risk of death, treatment failure and relapse. The aim of the present study is to study the clinical, radiological profile of pulmonary and extrapulmonary tuberculosis (EPTB) in HIV-seropositive patients.It was a prospective study conducted over a period of 1 year in the department of medicine, Pt B.D Sharma, PGIMS, Rohtak. We examined 100 HIV-infected patients with associated tuberculosis recruited from the department of medicine and antiretroviral center and were subjected to thorough clinical examination, X-ray chest, tuberculin testing and sputum examination for AFB and necessary relevant investigations for Extrapulmonary TB. Most common affected age group was 30-39 years. Pulmonary TB is the commonest form of TB in our study detected in 58 patients. Commonest Extrapulmonary TB was Tuberculosis lymphadenitis. Disseminated tuberculosis was only found in 4 patients Majority of lymph node TB was diagnosed by fine needle aspiration cytology (FNAC) examination. In present study, 64(64%) patients were cured from TB successfully. Defaulted/lost to follow-up constituted 12(12%) of patients. The results of this study provide information regarding the various forms of TB and their presentation in HIV-infected persons. Early diagnosis of tuberculosis and prompt institution of antitubercular treatment (ATT) reduces mortality and morbidity significantly. Therefore, adequate knowledge of the manifestations of tuberculosis in HIV-infected patients is absolutely necessary for optimal management and to reduce mortality and morbidity.
Authors and Affiliations
Dr. P. S. Ghalaut, Dr. Tarun, Dr. Santosh K. Dash, Dr. Jatin Ahuja
Keywords
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