Clinical Spectrum of Subclinical Hypothyroidism and its Management- A Prospective Observational Study
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 9
Abstract
Hypothyroidism is a common problem; it causes symptoms that reduce the functional status and quality of life. Subclinical hypothyroidism (SCH) describes a situation in which thyroid function is only mildly decreased, where the blood level of thyroxine remains within the normal range, but the TSH level in the blood is raised, which indicates mild thyroid failure or impending thyroid failure. Various causes are responsible for this type of medical scenario but the most common cause is chronic autoimmune thyroiditis followed by iodine deficiency, radiation therapy to head and neck region, use of drugs like lithium, amiodarone and unexplainable causes. Prevalence of SCH amounts to approximately 5-10%, being more frequent in women and with increasing prevalence with advancing age. Earlydiagnosis & treatment of subclinical hypothyroidism may prevent the onset of overt hypothyroidism and its associated effects. Our aim was to study the clinical spectrum of subclinical hypothyroidism and its management. All cases are diagnosed to have subclinical hypothyroidism with TSH > 4.0μIU/ml and normal T3, T4 Levels. This study was conducted over a period of one year; total subjects included were 155 and included patients with ages 18- 77 years. Weight gain is the dominant symptom in majority. Goiter was noted in 19 subjects. The patients with subclinical hypothyroidism with TSH level above 10 mIU/L should be managed with low dose thyroxine with proper follow up in order to minimize thyroid deficient related symptoms and signs. Keywords: Subclinical Hypothyroidism, Thyroid Stimulating Hormone, Goiter, Thyroxine, Auto-Immune Thyroiditis
Authors and Affiliations
Dr. Swaroopa Deme, Dr. Krishna Prasad Adiraju, Dr. Shetty Mallikarjuna, Dr. Ram Chander Torrem
Keywords
Related Articles
- EP ID EP371633
- DOI -
- Views 76
- Downloads 0
Study of demographic profile of unidentified dead bodies in central Mumbai region
Abstract: Mumbai tops the national charts in disposing of unclaimed bodies. Unidentified bodies impose great challenge to autopsy surgeon. In recent years there is increased in number of unidentified dead bodies in centr...
Obesity Related Adipokine Resistin Molecular Actions and Clinical Significance in Breast Cancer
Globally at present cancer and obesity are two greatest health concerns. Obesity and its metabolic complications have rapidly become major global health issues and are associated with increased risk for cancer, especiall...
Study of Liver Enzymes Especially Lactate Dehydrogenase to Predict Foetal Outcome in Pregnancy Induced Hypertension
The activity of liver enzymes, namely ALT, AST and LDH was evaluated in 68 cases of Pregnancy induced hypertension along with 56 normal primiparous subjects. The activity of all 3 enzymes were found to be elevated signif...
Congenital Adrenal Hyperplasia due to 21--Hydroxylase Deficiency in Saudi Arabia
Congenital adrenal hyperplasia (CAH) due to 21--hydroxylase deficiency is a common endocrine disorder accounting for more than 90 percent of CAH cases. As a result to the hormonal imbalance salt-wasting may occur, and...
Utility of MRI in Neonatal Hypoglycemic Brain Injury (NHBI) – Case Series
To assess the role of MRI in neonatal hypoglycemia, a prospective study was done on 10 neonates in the Department of Radiodiagnosis in Dr. D. Y. Patil Medical College and Research Centre, Pimpri, Pune, who were clinicall...