CLINICAL STUDY OF ANTERIOR SEGMENT FINDINGS IN PSEUDOEXFOLIATION SYNDROME
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 37
Abstract
Pseudoexfoliation syndrome (PEX) is a clinical entity characterised by the deposition of whitish-grey extracellular fibrins in the anterior chamber of the eye. It may complicate the cataract surgery. The aim of the study is to find out various anterior segment findings in patients having senile cataract with Pseudoexfoliation syndrome. MATERIALS AND METHODS A cross-sectional study was conducted from December 2015 to December 2016 by Ophthalmology Department, Prakash Hospital & Research Centre, Islampur. Patients with senile cataract attending Outpatient Department of Ophthalmology were included in the study. Complete clinical evaluation, with detailed slit-lamp biomicroscopy under maximal mydriasis with tropicamide 1% and Phenylephrine combination was performed. Undilated Gonioscopy was done in all cases. Diagnosis of PEX was based on the presence of grey flakes of PEX material on the anterior lens capsule or at the pupillary margin or both. Statistical analysis of the data was done by using Chi square test (χ2 test). The level of significance was fixed at p value less than 0.05, i.e. p<0.05 was taken as statistically significant. RESULTS Total 300 patients were evaluated for cataract surgery out of which 165 were female & 135 were male. 10% males (30) & 15% (45) females were having PEX. PEX was significantly more common in older age group. Incidence of nuclear cataract (86.66%) was significantly more in patients having PEX. PEX deposits on pupillary margin (80%), poor mydriasis (69.33%), & PEX deposits on anterior lens capsule (94.6%) were significantly observed (P<0.05%). IOP >21 mm was present in 26 (34.6%) cases. PEX deposits on trabecular meshwork was seen in 25 (33.33%) cases. Phacodonesis was present in 11 (14.6%) cases. Peripupillary atrophy was seen in 7 (9.3%) cases. Pigment dispersion was seen in 8 (6%) cases. Corneal endothelial deposits was seen in only one (1.3%) case. CONCLUSION Pseudoexfoliation syndrome is common in advanced age group. PEX material is commonly seen on pupillary border, anterior lens capsule, zonules and trabecular meshwork. Nuclear and hard cataract is commonly seen in these patients. Due to deposition of PEX material, resistance in pupil for dilatation, open angle glaucoma, & lens instability is common. All of these may complicate the cataract surgery and there is a need to take extra precautions in these patients prior to surgery.
Authors and Affiliations
Krishnadeo Nalawade, Smita Javadekar
Keywords
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- EP ID EP212036
- DOI 10.14260/Jemds/2017/654
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