“Clinical Study on Platelet Rich Plasma in Wound Healing”
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 2
Abstract
Introduction: wound management is a challenging task to the surgeon and a debilitating issue to the patients. The general treatment including the expert care in dressings, meticulous use of antibiotics, Negative pressure vacuum therapy dressings, surgical interventions and reconstructions using a lot of resources, expenses and expert hands. But the results are still unpredictable and unassured. Platelet-rich plasma (PRP) has a numerous number of growth factors, chemokines, cytokines and many other proteins which have a numerous number of properties out of which one is its role in wound healing. Materials and Methods: The PRP therapy consists of self-activated autologous platelet-rich plasma derived from centrifugation of whole blood by Double centrifugation method. It is given as a local subcutaneous infiltrate along the wound margins on every fourth day till the wound is completely healed with regeneration of skin or red healthy granulation tissue. The study consisted of 30 patients, ages ranging from 20 to 60, both males and femaleswho were studied from January 2017 to december 2018.Hb per cent below 9 was a contraindication. The wounds consisted of both acute and chronic, including compound fractures, infected wounds, non-healing ulcers. Results: 28 wounds were healed by this technique which did not require any further procedures and two of them required split skin grafting. The average number of sittings required were seven . Antibiotic cultures showed no bacterial growth during the course of treatment. Conclusion: platelet-rich therapy is a novel mode of treating wounds by their growth factor properties and antibacterial properties giving satisfying results without wasting resources nor need of any other complex and expert techniques in wound
Authors and Affiliations
Dr. Duvvuru Anvesh, Dr. Biju Ravindran
Keywords
Related Articles
- EP ID EP467587
- DOI 10.9790/0853-1802105356
- Views 55
- Downloads 0
“A Study of Use and Safety of Fibre - Optic Bronchoscope in Critically Ill Patients in Intensive Care Units at Our Tertiary Care Hospital.”
Introduction: fibre-optic bronchoscopy (FOB) is one of the most important techniques in pulmonary medicine. The diagnostic and therapeutic uses of FOB, with less morbidity and mortality have led to its increase use in cr...
Evaluation of Accuracy of Two Frequency-Based Electronic Root Canal Length Measurement Devices – An Ex Vivo Study.
The location of apical constriction is paramount for a successful endodontic therapy. Electronic apex locators operate on the basis of conductance of electricity through hollow tube. Useful when the apical portion of the...
Intramasseteric Cavernous Haemangioma: A Case Report.
Intramuscular haemangiomas (IMHs) of masseter muscle are extremely rare in head and neck region and often misdiagnosed as parotid tumours. We report a case of a 40 yrs old female who presented with a progressive non tend...
Prosthetic Management of an Ocular Defect – A Case Report
Magnificent and complex, eyes are the most important organ of the human body. An ocular defect has both psychological and physiological effect on the patient. A removable custom made or stock ocular acrylic prostheses is...
Comparitive Study of Blunt Dissection Vs Sharp Dissection in Open Elective Uncomplicated Inguinal Hernioplasty in GMKMCH, SALEM
.