“Clinical Study on Platelet Rich Plasma in Wound Healing”
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 2
Abstract
Introduction: wound management is a challenging task to the surgeon and a debilitating issue to the patients. The general treatment including the expert care in dressings, meticulous use of antibiotics, Negative pressure vacuum therapy dressings, surgical interventions and reconstructions using a lot of resources, expenses and expert hands. But the results are still unpredictable and unassured. Platelet-rich plasma (PRP) has a numerous number of growth factors, chemokines, cytokines and many other proteins which have a numerous number of properties out of which one is its role in wound healing. Materials and Methods: The PRP therapy consists of self-activated autologous platelet-rich plasma derived from centrifugation of whole blood by Double centrifugation method. It is given as a local subcutaneous infiltrate along the wound margins on every fourth day till the wound is completely healed with regeneration of skin or red healthy granulation tissue. The study consisted of 30 patients, ages ranging from 20 to 60, both males and femaleswho were studied from January 2017 to december 2018.Hb per cent below 9 was a contraindication. The wounds consisted of both acute and chronic, including compound fractures, infected wounds, non-healing ulcers. Results: 28 wounds were healed by this technique which did not require any further procedures and two of them required split skin grafting. The average number of sittings required were seven . Antibiotic cultures showed no bacterial growth during the course of treatment. Conclusion: platelet-rich therapy is a novel mode of treating wounds by their growth factor properties and antibacterial properties giving satisfying results without wasting resources nor need of any other complex and expert techniques in wound
Authors and Affiliations
Dr. Duvvuru Anvesh, Dr. Biju Ravindran
Keywords
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