A Retrospective Study of Nephrectomy Done At Bpkihs
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 12
Abstract
Purpose: To compare the efficacy and safety of combination of Tamsulosin and Solifenacin with Tamsulosin alone in improving the lower urinary tract symptoms of patients with indwelling double-J ureteral stents (DJS). Materials and Methods: A total of 70 patients with DJS were randomly divided into 2 groups. In group I (𝑛 = 35), all patients received combination of both tamsulosin 0.4 mg and solifenacin 10 mg daily and in group II (𝑛 = 35) all patients received tamsulosin 0.4 mg daily. All patients completed the International Prostate Symptom Score (IPSS), quality of life component of the IPSS (IPSS/Qol) and Visual Analogue Pain Scale(VAPS) questionnaire,before insertion, at 3rd day of stenting and at 2 weeks after stenting.Urine for Routine and microscopic examination and culture and sensitivity were sent on 3rd postoperative day or before the discharge of patient and sexual discomfort was assessed after 2 weeks of stent insertion. Results: The demographics and preoperative questionnaires scores of both the groups were comparable. There were statistically significant differences in all scores in favor of groups I as compared to group II. Group I showed statistically significant differences in total IPSS with P value <0.001, QoL score with P value <0.001, and VAPS score with P value <0.001. Patients were also evaluated after 2 weeks for sexual discomfort and found 4 (15.4%) patients with tamsulosin and solifenacin had discomfort whereas 22 (84.6%) patients receiving tamsulosin had discomfort which was statistically significant (P value <0.001). Conclusions: Combined therapy of tamsulosin and solifenacin significantly alleviated lower urinary symptoms associated with double-J stents as compared to tamsulosin alone.
Authors and Affiliations
Shah RS, Agrawal CS
Keywords
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- EP ID EP250611
- DOI 10.9790/0853-1612036977
- Views 57
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