A Double-Masked Comparison Of 0.1% Tacrolimus Ointment And 2% Cyclosporine Eye Drops As First Line Drugs in the Treatment of Vernal Keratoconjunctivitis
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 6
Abstract
This study was carried out to compare the efficacy of 0.1% Tacrolimus (FK-506) ophthalmic eye ointment with 2% Cyclosporine eye drops in the treatment of VKC. Two groups of VKC diagnosed patients was taken for study-Group A:36 patients received 0.1% tacrolimus eye ointment and Group B:36 patients received 2% cyclosporine eye drops. The study was conducted in Ophthalmology Department, Rajindra Hospital, Patiala. Patients fulfilling the inclusion criteria and after verifying the exclusion criteria were enrolled in the study. The main outcome measures were scoring and comparison of Total subjective symptom scores (TSSS) and Total objective ocular sign scores (TOSS) within and between the Groups at each follow up. With treatment both TSSS and TOSS decreased consistently in both groups without any adverse effects but an increase in scores was noticed within two weeks after drug withdrawl. Both drugs are equally effective and safe in VKC but with a short lasting effect.
Authors and Affiliations
Ekta Singla, Harsimran Singh, Navreet Kaur, Sachin Walia
Keywords
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- EP ID EP600544
- DOI 10.9790/0853-1606023035.
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