The Relationship among Demographic Factors, Treatment Modalities, Surgical Techniques, and Postoperative Complications in the Management of Esophageal Squamous Cell Carcinoma
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 6
Abstract
Background Surgery alone or surgery after neoadjuvant chemoradiotherapy or chemotherapy, often cause complications of varying degrees of severity. There seems to be an association between these complications and patient age, gender, as well as the treatment modalities and surgical techniques employed. This study investigated these probable relationships with regards to the current management of esophageal squamous cell carcinoma (ESCC). Methods A total of 245 ESCC patients who had received either neoadjuvant chemoradiotherapy or chemotherapy plus surgery or surgery alone, were recruited for this study. The relationships among patients’ demographic factors, treatment modalities, surgical techniques, as well as postoperative complications were analyzed. Results Two hundred and forty patients (98%) received surgery alone, 3 (1.2%) received neoadjuvant chemotherapy plus surgery, and 2 (0.8%) received neoadjuvant chemoradiotherapy plus surgery. Ivor-Lewis approach was the main surgical technique used. Pneumonia and pleural effusion were among the most frequent postoperative complications. There was a significant association between age and postoperative complications ( 2=10.194, P=0.017). Gender and postoperative complications also had a significant association ( 2=9.274, P=0.026). Neither age nor gender had a significant correlation with treatment modalities ( 2=1.297, P=0.523 and 2=1.348, P=0.510, respectively). Surgical techniques and postoperative complications had no significant relationship ( 2=9.308, P=0.409). Interpretations Age and gender are risk factors that determine the occurrence of postoperative complications. Patients can be offered any potentially good treatment irrespective of their age and gender. The surgical approach used may not be a risk factor to postoperative complications.
Authors and Affiliations
Godwin Botwe, Weifeng Tang, Michael Adu- Frimpong, Yusif M. Mukhtar
Diagnosis of Extra Pulmonary Tuberculosis By Using Xpert® MTB/RIF Assay (CBNAAT) And MGIT Liquid Culture.
Background: Globally, India Is A Home For More Than 25% Of Global Tuberculosis (TB) Burden. The Sensitivity Of Smear Microscopy And Its Inability To Detect Drug Resistance Limits Its Impact On TB Control. Early And Accur...
“Investigations on the Length of Hospital Stay of Orthopedic Patients – a study in a tertiary care hospital, Barisal, Bangladesh”
Treatment of the injured patients takes lot of time and energy all over the world and more so in our country with limited resources and manpower. We conducted an observatory study in Barishal Medical College Hospital in...
Appraisal of Clinical and Radiological Outcome of Management of Distal Tibia Fractures With Distal Tibia Locking Plate (DTLP)
Distal tibial fracture is one of the commonest fracture following accidents in over 15% of total fracture cases.The triumph key in managing these niggling fractures is to proficiently preserve, reconstruct the soft tissu...
Diagnostic Significance of Glenoid Fossa Position: A Cephalometric Study
Background: Diagnostic importance of glenoid fossa needs to be realized. A malocclusion can present itself with various features and a proper treatment demands an accurate diagnosis. Variability in location of glenoid fo...
Advances In The Management of Thyroid Eye Diseases -An Overview
Thyroid eye disease (TED) remains a notorious ailment for both patients and the treating ophthalmologists. Recent years have witnessed considerable research in the immunopathogenic mechanism of TED that has resulted in a...