Clinically silent pheochromocytoma in a female patient with androgenisation
Journal Title: Postępy Nauk Medycznych - Year 2013, Vol 26, Issue 11
Abstract
A 29-year-old female patient was admitted to the Endocrinology Department of CMKP due to androgenisation and hyperanrogeanemia; non-classic congenital adrenal hyperplasia (CAH) was suspected. The patient was diagnosed with polycystic ovary syndrome (PCOS). Low-grade hypertension (maximum 140/100 mmHg) and episodes of tachycardia at rest were observed. Diagnostic ultrasound revealed a tumor of the right adrenal gland, which was confirmed by magnetic resonance imaging (MRI): a tumor of 22 mm in diameter without infiltration and with small lipid content. Computed tomography (without contrast) showed a tumor of the right adrenal gland, 23 x 21 mm, with a density of 20 HU. The level of metanephrines in a 24-hour urine collection was normal and no abnormal tracer accumulation was shown in an MIBG scan nor somatostatin receptor scintigraphy. Due to the appearance of the tumor on MRI and slight clinical signs: brittle hypertension and episodes of tachycardia, pheochromocytoma was suspected and the patient was premedicated with phenoxybenzamine for laparoscopic adrenalectomy. On histopathological examination pheochromocytoma was confirmed.
Authors and Affiliations
Aleksandra Kruszyńska, Jadwiga Słowińska-Srzednicka, Maciej Otto
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