Clinician’s perspective for personalized medicine and genetic testing as the future of cancer diagnosis
Journal Title: Stanley Medical Journal - Year 2016, Vol 3, Issue 3
Abstract
Molecular diagnostics offer a promise of reducing the length, cost and uncertainty of new molecular entities and potentially unlocking targets for precision medicine through: patient susceptibility to disease; patient respond to treatment or any adverse events; disease progression; proof-of-concept targets correct pathway and success of treatment. Molecular diagnostic tests have emerged as one of the successful means for providing critical insights about disease diagnostics and treatment. The personalized medicine is becoming a reality not only for precise diagnosis but also providing targets towards development of successful therapy for cancer patients. To ensure that new therapies are delivered to the right patients through accurate diagnosis, it is essential to adopt the recommendations for molecular diagnostics as well as therapeutics. Molecular biomarkers can not only serve as predictive for clinical management of cancer but also provide a hope for targeted therapy. With the cost of genomic technologies coming down and results are more clinically relevant, it is possible to predict precise genetic variations that occur in cancer patients. However, awareness is required to reduce cost phenomenally altering cancer management in a better way. To make it reality consortium of oncologists is recommended for development of Indian patient specific biomarker study
Authors and Affiliations
Anita Ramesh, Subbu Apparsundaram, Karthikeyan Rajamani, Ramesh K Goyal
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