Clinico-Laboratory Profile of Vitamin B Deficiency in Children
Journal Title: GCSMC Journal of Medical Sciences - Year 2016, Vol 5, Issue 2
Abstract
Introduction: Nutritional vitamin B deficiency is common in developing countries and has a wide range of 12 neurological and hematological presentations. Aim: To study the clinical features and laboratory findings of vitamin B deficiency in children and correlate the findings with the severity of deficiency. Materials and Methods: 12 52 children between the age group 1month-6 years presenting with anemia and vitamin B deficiency were included 12 in this study. Their clinical findings and laboratory parameters were evaluated and correlated with the severity of vitamin B deficiency. Results: Out of the 52 patients enrolled 23 (44.2%) were boys and 29 (55.8%) were girls. 12 75% of children were in the age group 6 months to 2 years. All came from the lower socio-economic class. Deficiency was seen in children who had been breastfed by vitamin B deficient mothers, on inadequate 12 complimentary feeding and those on vitamin B deficient diets. 32 (61.5%) patients had severe vitamin B 12 12 deficiency. Apart from pallor, hyper pigmentation of knuckles (100%), hypo pigmented hair (100%), delayed development milestones (75%), tremors (37.5%), failure to thrive (31.2%) and generalized hypotonia, (25%) were the common features associated with severe vitamin B deficiency . 91.7% of patients with severe anemia had 12 severe vitamin B deficiency. Thrombocytopenia, leucopenia, pancytopenia, and macrocytosis were more 12 common in severe deficiency. Conclusion: Vitamin B deficiency was more common in children between the age 12 group of 6 months to 2years belonging to the lower socioeconomic class on a diet deficient in vitamin B . 12 Hematological and neurological manifestations were more common in those with severe deficiency. Early diagnosis and treatment is important to prevent hematological complications and neurological impairment in these patients. Preventive measures like dietary management and vitaminB supplementation have to emphasize.
Authors and Affiliations
Anuya Chauhan, Gargi Pathak, Mausam Shah
Keywords
Related Articles
- EP ID EP290509
- DOI -
- Views 53
- Downloads 0
Study of Pattern of Donor Deferral in Tertiary Hospital Blood Bank of India
Background: Blood transfusion saves millions of life all over the world every year. Shortage of blood donors has always been a problem throughout the world. In blood transfusion services many potential blood donors are d...
Nosocomial Infections (NIs) or Hospital Acquired Infections (HAIs)
Nosocomial Infections (NIs) or Hospital Acquired Infections (HAIs)
A study on Assessment of Knowledge and Attitude towards First Aid in Road Traffic Accidents among College Students of Ahmedabad city, India
Introduction: Fatalities and injuries resulting from road traffic accidents (RTA) are a major and growing public health concern in India. The knowledge of first aid amongst medical students and general public has always...
Sonographic Measurement of Inferior Vena Cava Diameters and Its Usefulness during Resuscitation of Patients with Trauma
Introduction: Hemorrhagic shock is the leading etiology in most cases of trauma and can be rapidly fatal. Thus adequate fluid resuscitation is required to improve the outcome of patients. CVP is usually used to guide res...
Protein Expression of p53 and CD44 in Patients with Cancer of Buccal Mucosa
Background: Methods: Conclusion: In India, the incidence of cancer of buccal mucosa is a serious public health issue where a large fraction is related to the poor treatment outcome. Identification of high-risk oral prema...