CLINICO MICROBIOLOGICAL PROFILE AND ANTIBIOTIC RESISTANCE ANALYSIS OF DIABETIC FOOT ULCER FROM A TERTIARY CARE HOSPITAL
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 71
Abstract
BACKGROUND Diabetic foot ulcer (DFU) is a common complication of diabetes mellitus accounting for 30% of hospital admissions among diabetics. If not treated appropriately DFU infection complicates as amputation, sepsis and even mortality. Knowledge about local microbiological profile with their resistance pattern are essential for every institute to aid in formulating antibiotic policy, thus reducing the economic burden and improve the quality of life. MATERIALS AND METHODS A total of 100 in-patients with DFU of Grade 2 and above as per Wagner’s classification were included in our study. After obtaining the informed consent exudates, tissue biopsy or swabs were collected in a sterile container and further processed in microbiology lab. RESULTS All were male participants with mean age of 56.32 years; 74% had mean diabetic duration of 8.2 years. Common predisposing factors were neuropathy, trauma; 54% had single and 46% had multiple ulcers. Even though many on regular treatment for diabetes, DFU as a complication is increasing. Total of 80% (80/100) were culture positive yielding 92 isolates, of which Gram negative organisms (72/92) were predominant; 15% (12/80) were polymicrobial. Pseudomonas aeruginosa was the commonest isolate in both single and multiple ulcer emphasising that non-fermenting Gram negative bacilli are in a raising trend. Among our isolates, 40% were Methicillin resistant Staphylococcus aureus, 47.3% were carbapenem resistant Enterobacteriaceae and 80% of Acinetobacters were multidrug resistant. CONCLUSION Local microbiological profile, resistance pattern, proper wound care will significantly diminish the complications of DFU and also aid in formulating the Institutional antibiotic policy
Authors and Affiliations
Ramesh Arunagiri, Raja Sundaramurthy, Arunkumar Viswanathan, Vithiya Ganesan, Rajendran Thiruvannamalai
Keywords
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- EP ID EP265518
- DOI 10.14260/Jemds/2017/1100
- Views 85
- Downloads 0
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