Clinico-pathological analysis of primary breast lymphoma: A cross sectional study in a tertiary care hospital
Journal Title: IP Journal of Diagnostic Pathology and Oncology - Year 2018, Vol 3, Issue 1
Abstract
Introduction Breast being welldeveloped mammary organ in females is a common site for many nonneoplastic and malignant lesions due to varied underlying etiopathogenesis Lymphoma being a malignant clonal proliferation of lymphoid cells primary breast lymphoma is an unusual entity with nonepithelial origin characterized by florid proliferation of neoplastic lymphoid cells With uncertain etiology the clinical presentation is vague with varied radiological and histopathological patterns In the present study we analyzed the incidence of primary breast lymphoma with a study on clinicohistopathological pathological spectrumMethodology The study was conducted retrospectively and included patients with breast lesions and the histopathological evaluation from their subsequent tissue biopsies All the clinical data was documented and cytological correlation were done in available cases Hematological and radiological interpretations are analyzed subsequently as preop work up of the patients Clinicopathological analysis of the results were done based on knowledge from research worksResults and Observation The seven years retrospective study included nine cases which fell into the criteria of PBL with average age incidence between 4th amp 5th decade occurring retroareolar region with right breast preponderance Radiological studies picked up malignancy only in few cases but categorization of lymphoma were not reported by imaging Hematological parameters showed anaemia leucopenia and pancytopenia depending on extent and involvement of the bone marrow Histomorphology and subsequent IHC expression stayed gold standard role in diagnosis compared to radiological interpretationsConclusion Primary breast lymphoma is rare type of breast cancer with varied presentation Any patient presenting with solitary lobulated breast lump in 5th decade PBL should be kept as one of the differentials especially with anaemia and axillary node enlargement Clinicohematological correlation with subsequent histomorphology helps the Pathologist is diagnosing the condition thereby aiding the in Prompt managementnbsp Keywords Breast Lymphoma Hematological parameters Histopathology IHC Radioimagingnbsp
Authors and Affiliations
Anandraj Vaithy, Shanmugasamy, Dhananjay Kotasthane
Keywords
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- EP ID EP482721
- DOI 10.18231/2581-3706.2018.0001
- Views 101
- Downloads 0
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