Clinico-pathological profile of male breast cancer treated in a regional cancer centre of North West India
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 11
Abstract
Introduction: Male breast cancer is rare malignant neoplasm and accounts for less than 1% of all breast cancer. The present study is aimed at finding the incidence, the age profile and the histological types with receptor status of male breast cancer cases treated in a Regional Cancer Centre in north west India. Material and methods: We reviewed the records of all male breast cancer(MBC) patients registered in our centre from January 2014 to December 2017. Clinicopathological profile like age, histopathological pattern, TNM staging and receptor status were analysed. Results: Total 60 MBC patients were registered in our centre between January 2014 to December 2017. The mean age of presentation was 59.08 years and median age of presentation was 46.5 years. Out of 60 cases 34 (57%) were found to be in advanced stage i.e. stage III followed by 22 (38%) cases in stage II. Most common presentation was ulcer in breast followed by swelling in axilla. Other than common invasive duct carcinoma few uncommon variants like mucinous and metaplastic were also found. In 86% patients receptor status was ER +ve, PR +ve and HER-2 neu –ve followed by ER +ve, PR +ve and HER-2 neu+ve (4%). Conclusion: Male breast cancer is found to be at mean age of 59.08 but median age of 46.5 years . The incidence in younger age group is considerable. The histological nature of disease is mostly invasive duct carcinoma and most commonly seen hormone status is ER +ve PR +ve and HER- 2 neu –ve at our centre.
Authors and Affiliations
Narendra Kumar Gupta
Keywords
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