Clinico-Pathological Study of Brain Tumors with Special References to Atypical Cases: A Retrospective Analysis of 130 Cases in a Tertiary Care Hospital in India
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 3
Abstract
Context: Brain tumors are heterogeneous group of neoplasms, which can occur at any age. Despite of some published articles regarding pathological pattern of brain tumors from different parts of the world and in India, comprehensive clinic-pathological studies regarding atypical brain tumor cases from Eastern India is lacking. Aims: Aims of the present study was to study of clinical and histopathological spectrum of brain tumors and discuss the clinical, radiological, squash cytology and histopathological aspects of atypical cases. Settings and Design: We have approached every cases of brain tumor, diagnosed during the study period. Radiological, clinical and squash cytology data were correlated with histomorphology for correct diagnosis and analysis of atypical cases. Methods and Material: The study was a cross-sectional observational study involving 130 cases of brain tumor, diagnosed during the three years study period (Jan, 2010-Dec, 2012). Data on clinical, radiological features of the cases were collected from all patients. Histopathological diagnosis was correlated with clinico-radiological diagnosis. Atypical cases were reviewed further with squash cytology and radiological data. Results: We evaluated 130 cases of brain tumor with a male preponderance. Most common type tumor was neuroepithelial tumor (92 cases, 70.76%), among which, most frequent subtype was astrocytic tumors (54 cases, 41.5%). Second most frequent brain tumor was meningioma (20 cases, 15.3%). We found four atypical cases as rosette forming glioneural tumor, rhabdoid meningioma, primary melanoma of brain and congenital mature teratoma respectively. Conclusions: Astrocytic tumors are most common subtype. However WHO grade I neoplasms are more frequent brain tumors. Though rare, the atypical cases need radiological, squash cytology, histology and immunohistochemical collaboration for correct diagnosis.
Authors and Affiliations
Rajashree Pradhan, Sajeeb Mondal, Subrata Pal, Shrmistha Chatterjee, Arindam Bandyapadhyay, Debosmita Bhattacharyay
Keywords
Related Articles
- EP ID EP547821
- DOI 10.21276/ijmrp.2017.3.3.030
- Views 95
- Downloads 0
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