Clinicohematological Profile of Pancytopenia: A Study from a Tertiary Care Hospital

Journal Title: Dicle Tıp Dergisi - Year 2016, Vol 43, Issue 1

Abstract

Objective: Pancytopenia is a clinicohematological prob­lem with wide spread discriminated diagnosis. A through evaluation of patient is necessary to identify the cause as large number of patients has reversible etiology and early diagnosis may be lifesaving. Diagnosis of pancyto­penia requires microscopic examination of bone marrow aspirates to assess the overall cellularity and morphol­ogy. This study was conducted with the aim to find out the cause of pancytopenia on the basis of bone marrow findings. Methods: The present study was conducted in the de­partment of pathology over a period of one year. A total of 169 patients were included in the study that fulfilled the criteria of pancytopenia. A detailed clinical history and physical examination followed by complete blood count, peripheral smear examination and bone marrow aspira­tion was done in all cases. Results: There was slight male predominance with male to female ratio of 1.2:1. The majority of patients were in second and third decade. The main cause of pancytope­nia was megaloblastic anemia followed by mixed nutri­tional deficiency anemia and others. Conclusion: This study emphasized that in developing countries like India majority of the patients had reversible etiology and patients can be put on a trial of hematinics and close haematological follow up. Key words: Pancytopenia, bone marrow, megaloblastic anemia, aplastic anemia

Authors and Affiliations

Monika Gupta, Abha Chandna, Sanjay Kumar, Sant Kataria, Sonia Hasija, Gajender Singh, Rajeev Sen

Keywords

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  • EP ID EP149025
  • DOI 10.5798/diclemedj.0921.2016.01.0629
  • Views 113
  • Downloads 0

How To Cite

Monika Gupta, Abha Chandna, Sanjay Kumar, Sant Kataria, Sonia Hasija, Gajender Singh, Rajeev Sen (2016). Clinicohematological Profile of Pancytopenia: A Study from a Tertiary Care Hospital. Dicle Tıp Dergisi, 43(1), 5-11. https://europub.co.uk/articles/-A-149025