Clinicopathological analysis of 55 cases of ocular surface squamous neoplasia
Journal Title: Tropical Journal of Ophthalmology and Otolaryngology - Year 2016, Vol 1, Issue 1
Abstract
Introduction: The aim of this observational study is to review the presenting clinical features and histopathology of 55 cases of OSSN, at a tertiary care institute in Western India. Method: The study enrolled patients from the in-patient department. The workup included a detailed history with Slit-lamp examination, clinical photographs and histopathological analysis of tissue samples taken via incisional or en-block excisional biopsy. Results: The mean age of the patients was 38.2 years. 25.4 % of patients were HIV reactive, with an average age of 26.8 years. The most common presenting complaints were redness, watering and foreign body sensation occurring in 59.9% of the cases. 29% patients were asymptomatic or presented with complaints of a whitish mass lesion. Morphologically, the commonest lesion was of the Leukoplakic variety (32.72% of cases). On histopathological analysis, 41.8% of cases showed intraepithelial carcinoma, with mild dysplasia in a majority of cases. Invasive carcinoma was seen in 58.18% of cases, with poorly differentiated cells in a majority of them. Conclusion: We conclude from the study that the affected population is younger in our region of the world, than in the West. HIV screening would help identify occult cases of HIV which present only with OSSN. Increased awareness of this disease among ophthalmologists would help ensure an early and definitive diagnosis.
Authors and Affiliations
Ruchi C Kabra, A Morawala, V N Maheshwari
Keywords
Related Articles
- EP ID EP229820
- DOI 10.17511
- Views 188
- Downloads 0
Visual acuity in patients with retinitis pigmentosa
Objective: The present study is taken up to learn the visual acuity in patients with retinitis pigmentosa (RP). Methods: The current study was conducted in thirty male and female patients with in age group of 30-50 years...
Congenital Dacryocystitis- Clinical Profile and Outcome
Aim: To assess the clinical and epidemiological profile of congenital dacryocystis and its treatment outcome. Material and Methods: A prospective study was conducted for duration of two years, cases with congenital dacry...
A rare case of congenital corneal clouding with anterior staphyloma of the eye
There are only few case reports of congenital anterior staphyloma, an extremely rare condition. We report a case of congenital anterior staphyloma presenting as corneal clouding. A preterm girl baby was noted at birth to...
The clinical enigma of a Midfacial Destructive lesion
Midfacial destruction is a rare presentation of various neoplastic, autoimmune and infective disorders. Here we present a rare case of a midfacial distructive lesion in a young patient with xeroderma pigmentosum, which w...
Neonatal EEG- an overview
Electro-encephalogram (EEG) is the best non-invasive modality for brain monitoring. As brain continues to develop and mature in neonatal period, EEG of a normal newborn varies from time to time. Wave patterns may be norm...