CLINICOPATHOLOGICAL CHARACTERISTICS OF 38 PATIENTS WITH STAGE I HIGH-GRADE SEROUS OVARIAN CANCER WHO RECEIVED ADJUVANT CHEMOTHERAPY
Journal Title: Kocatepe Medical Journal - Year 2022, Vol 23, Issue 3
Abstract
OBJECTIVE: Epithelial ovarian cancer is the most mortal among female cancers and is mostly diagnosed at an advanced stage It was aimed to investigate the clinicopathological features and recurrence patterns of patients who were diagnosed with stage 1 high-grade serous ovarian cancer and received adjuvant chemotherapy after surgery. MATERIAL AND METHODS: Thirty-eight high-grade serous ovarian cancer patients treated in our clinic, stage 1 patient who underwent total abdominal hysterectomy + bilateral salpingooferectomy + pelvic-paraaortic lymph node dissection +/- omentectomy were included in the study. RESULTS: Regarding the stage distribution of the patients, Stage IA 10 patients (26.3%), IB 7 patients (18.4), IC1 5 patients (13.2%), IC2 11 patients (28.9%), IC3 5 patients (13%) , 2). Recurrence developed in 11 (28.9%) of 38 patients. Regarding the recurring regions of the patients with recurrence, only pelvic 1 (2.6%), only the abdomen 8 (21.1%), while abdominal + pelvic recurrence developed in 1 (2.6) patient. CONCLUSIONS: Serous histology is the most common subgroup of epithelial ovarian cancers and usually diagnosed at an advanced stage. The relapse rate is also high in patients diagnosed at an early stage.
Authors and Affiliations
Caner ÇAKIR, Rıza DUR, Betül TOKGÖZ, Doğukan ÖZKAN, Çağatayhan ÖZTÜRK, Fulya KAYIKÇIOĞLU, Vakkas KORKMAZ
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