Clinicopathological Correlation of Thyroid Cytology with Thyroid Function Tests: A Study of 100 Cases
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2017, Vol 6, Issue 4
Abstract
Background: Thyroid Swellings are most common in routine clinical practice. Fine needle aspiration cytology (FNAC) gives quick results with good sensitivity and specificity. It minimize further investigations and surgeries. Combined approach of Thyroid functions test (TFT), FNAC and Histopathological findings will increase the specificity for the diagnosis of thyroid lesions. Aims & Objectives: Study aims to correlate cytological findings, TFT and Histopathological findings. Materials and Methods: The present study was undertaken in Department of Pathology, KBN institute of Medical Sciences, Kalburagi from June 2016 to May 2017. Total of 100 cases presented with Thyroid swellings, who underwent FNA and TFT . Among 100 cases, 25 cases had Histopathological Follow Up. Results: Total of 100 patients with thyroid swellings were included in this study. 90 females and 10 were males. Maximum patients were in age group of 21–30 years. Most Common Lesions were Non-Neoplastic accounting 88 % of cases, among these Colloid Goitre was commonest. 12% cases were found to be neoplastic, among these, Follicular Neoplasm were the most common, followed by Papillary Carcinoma. 70 % were Euthyroid, 2 % were Subclinical hyperthyroid, 16% were hypothyroid, 5% were hyperthyroidism and 7 % were subclinical hypothyroidism. Among these 25 cases had histopathological Examinations, 21 were correlated with cytological studies, 2 were false Negative and 1 was False positive . So, the sensitivity of FNAC was 83.3%, Specificity was 91.6% and Accuracy was 84%. Conclusion: FNAC gives High accuracy and specificity for further management of Thyroid lesions. All the FNA diagnosis must be viewed in the light of the clinical picture and thyroid hormone profile to minimize the risks of false negative reports.
Authors and Affiliations
Kumari Jyothi Vibhute
Keywords
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- EP ID EP467847
- DOI 10.21088/ijprp.2278.148X.6417.2
- Views 69
- Downloads 0
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