Cytomorphological Patterns of Tuberculous Lymphadenitis in Correlation with AFB Positivity
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2017, Vol 6, Issue 2
Abstract
Objective: Despite progress in prophylaxis and treatment modalities, tuberculous (TB) lymphadenitis still remains a major health problem in developing countries. In India, extrapulmonary TB accounting 20% of all TB cases and its prevalence in the country varies between 8.3% and 13.1%. The aim of this study was to describe various cytological pictures of tuberculous lymphadenitis with their relative frequency and to assess correlation between Fine needle aspiration cytology (FNAC) and Ziehl-Neelsen (Z-N) staining in diagnosing tuberculous lymphadenitis. Materials and Methods: A total of 132 cases with cytological proven tuberculous lymphadenitis were taken up for the study. Details such as age, sex, group of lymph nodes involved, type of aspirate, cytomorphological patterns and Acid fast bacilli (AFB) positivity on ZN staining were analysed. Results: The sites of distribution of lymphadenopathy were as follows: Cervical lymph nodes – 109, Axillary – 21, Inguinal lymph nodes – 02. Cytological patterns in all 132 cases were as follows: Pattern A – 22, Pattern B – 73, Pattern C – 37 cases. On grading of AFB positivity, Grade 1+ observed in 22.7%, Grade 2+ observed in 31.6% 2, and Grade 3+ observed in 45.5% cases. Conclusion: FNAC is a simple, cost effective and minimally invasive technique to diagnose tuberculous lymphadenitis. Since granuloma formation is not often seen in purulent aspirate, ZN staining must be done to rule out tuberculous lymphadenitis.
Authors and Affiliations
Janarthanam Venkatraman
Keywords
Related Articles
- EP ID EP462935
- DOI 10.21088/ijprp.2278.148X.6217.14
- Views 104
- Downloads 0
Histopathology and Clinical Correlation of Tortion of Ovary
Ovarian cysts and tumours are the major problems in women. Vast majority of ovarian cysts are benign in nature. Ovarian cysts are usually asymptomatic, they are found as an incidental finding during routine ultasonogram....
Malignant Mixed Mullerian Tumour of Ovary: A Case Report
Malignant Mixed Mullerian tumour (MMMT) of ovary is a rare, neoplasm accounting for less than 1% of all ovarian cancers. They are histologically biphasic tumours with both carcinomatous (epithelial) and sarcomatous (stro...
Role of Fine Needle Aspiration Cytology in Diagnosing Soft Tissue Tumors : A Study of 653 Cases
Introduction: Fine needle aspiration cytology (FNAC) is a useful diagnostic modality in soft tissue lesions. However an exact cytological diagnosis is often difficult due to constraints of recognizable tissue architectur...
Comparison of Morphine with Nalbuphine as an Adjuvant to Caudal Bupivacaine: A Double blinded Randomized Study
Context: Caudal analgesia is the most preferred technique for pain relief in paediatric population using local anaesthetic drug along with other adjuvants such as morphine, fentanyl, nalbuphine, tramadol, clonidine. Aim...
Histological Detection of Helicobacter Pylori: Comparison of Giemsa and Immunohistochemistry Techniques in Gastric Adenocarcinoma Specimens
Background: The various histological methods of identification of Helicobacter pylori have different sensitivity and specificity with varying strengths and weaknesses in terms of cost and convenience. Aim: The aim of thi...