Correlation of Malaria Parasite Density with Blood Cell Counts: A Study in an Endemic Region of Northern India
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2019, Vol 8, Issue 1
Abstract
Malaria is an important public health concern especially in endemic nations like India. Hematologic changes play a major role in fatalities. The present study was conducted with an objective to assess blood cell counts in malaria and correlate them with parasite density, so as to enforce their role as indicators of disease severity. A total of 144 malaria positive cases diagnosed at JN Medical College and Hospital, Aligarh during the period from November 2014 to October 2015 were included in this study. Complete blood cell count was assessed along with peripheral blood smear examination of each patient for parasite identi cation and calculation of parasite density. The results were statistically analyzed using SPSS version 19. A signi cant decreasing trend of haemoglobin concentration, leukocyte count and platelets was noted with increasing parasite density (p < 0.001). Eosinophilia was also a key nding. In conclusion, a spectrum of deranged blood parameters such as a low leukocyte count and eosinophilia along with anemia and thrombocytopenia may serve as a basis for immediate and aggressive treatment approach in severely febrile patients of malaria.
Authors and Affiliations
Nausheen S. Khan
Keywords
Related Articles
- EP ID EP596894
- DOI 10.21088/ijprp.2278.148X.81219.11
- Views 79
- Downloads 0
Endometrial Cyst of Pancreas
Endometriosis is a benign condition characterized by the presence of endometrial tissue outside the endometrial cavity. It is usually confined to the pelvis and reproductive organs, but has been described in the omentum,...
Study on Quick Score of Hormone Receptor Status of Breast Carcinoma
Introduction: Breast acer is a common cancer in Indian population. The assessment of estrogen receptor (ER) status of breast carcinoma is a routine practice to predict the likely outcome of endocrine therapy. The assessm...
Expression of p63 in Benign, In-Situ and Invasive Ductal Carcinoma of Breast
Background: p63 is a member of p53 family of transcription factors which have important function in tumorogenesis and oncogenesis. It is involved in cellular differentiation and exposed in nuclei of myoepithelial cells o...
Clinicopathological Evaluation of Uterine Sarcomas: An Institutional Experience
Introduction: Uterine sarcomas are highly malignant tumors accounting for 3-7% of all uterine malignancies. According to the World Health Organization, uterine sarcomas consist of two main categories: mesenchymal tumours...
Histopathological Study of Non-Neoplastic Space Occupying Lesions (SOLs) of Central Nervous System: A Study from a Tertiary Care Centre
Introduction: Unlike in other systems, CNS has predominantly neoplastic lesions in comparison with the non-neoplastic ones. However, non-neoplastic CNS lesions are a mimicto neoplastic lesions posing histopathological di...