Clinicopathological Evaluation Of Portal Hypertensive Colopathy In Cirrhotic Patients
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 5
Abstract
Aim: The aim of this study was to evaluate the colonoscopy findings in Patients with Cirrhosis Portal Hypertension and Histopathologic correlation of those colonoscopy lesions. The prevalence of portal hypertensive colopathy was evaluated, the lesions were biopsied and specimen sent for Histopathologicexamination. The prevalence of Portal Hypertensive colopathy were correlated with severity of Liver Disease. Methodology: Cases of Cirrhosis with Portal Hypertension presenting to the Medical Gastroenterology Department, were included in the study. Symptomatic Patients were subjected to White Light Colonoscopy. Lesions characteristic of Portal Hypertensive Colopathy were studied. Those lesions were biopsied and specimenwere subjected to Histopathological Examination. Results:In a study of 100 cases of cirrhosis, portal hypertensive colopathy was present in 61 patients (61%), including solitary vascular ectasia in 30 patients (30%) and diffuse vascular ectasia in 41 patients (41%).Histological study revealed a marked dilatation in the microcirculation at the level of the ascending colon and rectum. The Child - Pugh class was correlated with a severity of portal hypertensive colopathy. Platelet count and history of Alcohol intake was significantly associated with portal hypertensive colopathy. Conclusion: A history of alcohol intake was the main cause of liver cirrhosis. As the Child – Pugh class worsens and platelet count decreases, the prevalence of portal hypertensive colopathy increases in patients with liver cirrhosis. Though the histopathologicevaluation had characteristiclesions, which correlated with Endoscopic findings.it did not correlate with the severity of Liver Disease. Hence acolonoscopy examination is indicated, especially those with worsening Child- Pugh class and or decreasing platelet count but a routine Histopathological examination is not indicated.Other incidental findings in colonoscopy and histopathology was also made out during the study.
Authors and Affiliations
Malarvizhi Murugesan, Jamila Alagarsamy, S. Selvi, ArcotRajeswaran Venkateswaran, M. S. Revathi
Keywords
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- EP ID EP598152
- DOI 10.9790/0853-1605112125.
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