CLINICOPATHOLOGICAL EVALUTION OF NATIVE KIDNEY BIOPSIES IN CHILDREN
Journal Title: Kocatepe Medical Journal - Year 2023, Vol 24, Issue 4
Abstract
OBJECTIVE: It is aimed to evaluate kidney biopsies, which is an important diagnostic method in the evaluation of renal parenchymal diseases. MATERIAL AND METHODS: In this study, native kidney biopsies performed on 333 pediatric cases were evaluated. Biopsies were performed using semiautomatic and fine (16-18 G) needles. RESULTS: The most common biopsy indication was proteinuria and hematuria, and the most common pathological diagnosis was normal biopsy results including minimal lesion disease. No complications were observed during or after the biopsy. The mean number of glomeruli was 27.1±17.8, the rate of detection of sufficient number of glomeruli was 81.4%, the rate of detection of borderline sufficient glomeruli was 8.4%, and the rate of detection of insufficient number of glomeruli was 10%. Compared to the biopsies performed without ultrasonography, the mean glomeruli count was higher and the rate of insufficient glomeruli was lower in 28.2% of the cases who underwent ultrasound-guided biopsy (31.5±18.1 vs 25.4±17.5 ; 2.1% vs 13.3%). CONCLUSIONS: Kidney biopsy is a diagnostic method that can be easily performed in children with or without USG, using automatic and fine needles, and has a low complication rate. The rate of obtaining sufficient glomeruli is higher in biopsies performed with ultrasonography, and biopsy should be performed with ultrasound guidance whenever possible.
Authors and Affiliations
Şükran KESKİN GÖZMEN Erkin SERDAROĞLU Nida DİNÇEL Pınar ERTURGUT Cemaliye BAŞARAN Fatma DEVRİM Özlem DUR Betül PEHLİVAN ZORLU Mehmet COSKUN Malik ERGİN
Keywords
Related Articles
- EP ID EP722686
- DOI https://doi.org/10.18229/kocatepetip.1089739
- Views 20
- Downloads 0
DNA BINDING ACTIVITIES OF THE VINCA ALKALOIDS AND PACLITAXEL AS ANTI-MICROTUBULE DRUGS USED IN CANCER THERAPY
OBJECTIVE: Microtubules are an essential part of the intracellular cytoskeletal structure and possess unique polymerization dynamics that are critical for many cellular functions, including cell division. Anti-microtubul...
THE CAUSE OF THE RELATIONSHIP BETWEEN PROSTATE SPECIFIC ANTIGEN AND RENAL FUNCTION ASSOCIATED PARAMETERS: AGE
OBJECTIVE: It was aimed to investigate the relationships between creatinine, estimated glomerular filtration rate (eGFR), urea, uric acid and prostate specific antigen (PSA) levels, that are used in screening, diagnosis...
A COMPARISON OF THE HEALTHY LIVING BEHAVIORS OF STUDENTS EDUCATED IN THE FIELD OF HEALTH
OBJECTIVE: It was aimed, in this study, to make a comparison of healthy living behaviors of students studying in different branches of the health field. MATERIAL AND METHODS: The study was carried out with 490 students...
ASSESSMENT OF CASES ADMITTED TO THE NEONATAL INTENSIVE CARE UNIT WITH LOWER RESPIRATORY TRACT INFECTION
OBJECTIVE: The purpose of this study is to assess the clinical features, laboratory findings, diagnosis and treatments of neonates in the neonatal intensive care unit with a diagnosis of lower respiratory tract infection...
EFFECTS OF AGMATINE SUPPLEMENTATION AND AEROBIC EXERCISE ON SPATIAL LEARNING IN AGED RATS
OBJECTIVE: The aim of the study is to examine the effects of agmatine supplementation and exercise on cognitive functions of aged rats. MATERIAL AND METHODS: In the study, 36 healthy, old male Sprague-Dawley rats with a...