Clinicopathological study of ABO blood types in prostate cancer
Journal Title: Indian Journal of Pathology and Oncology - Year 2018, Vol 5, Issue 4
Abstract
Aim To study the association between the ABO blood groups and clinicopathological features in cases of prostate cancer PCaMaterials and Methods Fifty cases of PCa diagnosed on transurethral resection of prostate chips were a part of the study Cases were classified into low risk and high risk categories and these categories were compared with the clinicopathological features and ABO blood groupsResults In the study of 50 cases 44 cases belonged to the high risk category with 3375 patients being of non O blood group and 1125 being of the O blood group Patients of non O group had an increased risk of aggressive PCa on comparison with the blood type O Chi sqaure test showed no significant difference between the non O and O groups regarding PSA value Gleason score tumor stage node positivity and bone metastasis individually p0418 p0967 p0506p0775 p0549 However within the high risk category a statistically significant value was found for non O blood group against O groups p004 which was further proven by regression analysisConclusion In this study non O blood types especially A and B but not AB were found to be independent predictors for high risk PCa and O blood type patients had a low risk of aggressive PCa thus emphasising the importance of blood typing in patients with PCa Keywords Prostate cancer PCa ABO blood type O blood type Non O blood type
Authors and Affiliations
Sushma Shankar, CSBR Prasad
Keywords
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- EP ID EP475957
- DOI 10.18231/2394-6792.2018.0129
- Views 57
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