Clinicopathological study of neoplastic and non-neoplastic lesions of prostate- two years study
Journal Title: Indian Journal of Pathology and Oncology - Year 2017, Vol 4, Issue 4
Abstract
Introduction: Among the cancer related deaths in men, prostatic cancer is the second most common to lung cancer. Important cause for prostatic morbidity and mortality includes inflammation, benign nodular enlargement and tumors. Histopathological diagnosis and grading plays a definitive role in the management of prostatic cancer. The current study aims at analyzing clinicopathological features of various neoplastic and non-neoplastic lesions of the prostate. Materials and Method: The present study included 158 prostatic specimens, which comprises of 157 TURP chips, and 1 prostatectomy specimen. The results were grouped into non-neoplastic and neoplastic lesions. The cases of prostatic adenocarcinoma were graded using Gleason microscopic grading. Results: Out of 158 prostatic specimens studied; 145 were benign lesions, 4 were premalignant and 9 were malignant lesions. Among benign lesions nodular hyperplasia without prostatitis was the most common. The cancer detection rate with prostatic volume < 40 ml was higher than with >40 ml. Most malignant prostatic lesions showed marked elevation in serum PSA levels (>20 ng/ml). Among the malignant lesions, commonest lesion was prostatic adenocarcinoma. Discussion: Since low-grade lesions are usually asymptomatic, awareness of serum PSA level estimation, digital rectal examination should be done among elderly males who are prone for malignancy. Male individuals with a positive family history for prostatic carcinoma must undergo relevant screening test.
Authors and Affiliations
SD Birare, SK Mahule, KT Dalve, NR Patil, NV Naigaonkar
Keywords
Related Articles
- EP ID EP318130
- DOI 10.18231/2394-6792.2017.0133
- Views 50
- Downloads 0
To evaluate the role of cellular swirls in fine needle aspiration cytology diagnosis of papillary carcinoma thyroid
Objective: To enhance the diagnostic accuracy of papillary carcinoma thyroid by evaluating nuclear and architectural features on cytology with address about the details of cytologic pitfalls. Study Design: 14 cases of pa...
Clinico-histomorphological spectrum of abnormal uterine bleeding
Introduction Abnormal uterine bleeding is considered as one of the most common and perplexing problems both to the patient and gynecologist Histopathological diagnosis of organic cause of menorrhagia plays an important f...
Histopathological overview of central nervous system tumours in North Maharashtra, India: a single center study
Background: Central nervous system (CNS) tumor are considered as most notorious in all types of cancers. Incidence of CNS tumors in developing countries is lower as compared to developed countries, but increased rate has...
Efficacy of cell block immunocytochemistry in the diagnostic workup of non hodgkin lymphoma-experience from a tertiary care hospital in North India
The WHO 2016 update on lymphoid neoplasms incorporates criteria independent of tissue architecture in the diagnosis and subclassification of nonHodgkin lymphoma Thus lymphoid neoplasms with characteristic immunophenotype...
Embryonal rhabdomyosarcoma in a 1 year old boy misdiagnosed as myxoma in histopathological examination- A case report
Introduction: Rhabdomyosarcoma (RMS) is a rare tumor, with an annual incidence of 4.3 cases per million children. The orbit is the primary site in approximately 10% of these tumors. RMS is the most common malignant orbit...