Clinicopathological study of recipients’ corneal tissue excised during penetrating keratoplasty. Best out of waste!
Journal Title: IP Archives of Cytology and Histopathology Research - Year 2018, Vol 3, Issue 3
Abstract
Introduction Corneal buttons removed during penetrating keratoplasties PK from recipients which were routinely discarded were studied with aim to analyze the common indications of PK and changing pattern of corneal diseases in developing countries like IndiaMaterials and Methods This is an observational case series carried out in tertiary care hospital of central India from October 2012 to October 2014 Histopathology of 156 corneal tissues was done of which 75 were recipients corneal tissues removed during PK and 81 were residual adjacent donors corneal tissues left out after corneal button was removed for transplantResults The most common indication of PK in our study was corneal ulcer n37 4933 followed by infectious keratitis n22 2933 which included ulcers in various stages of healing and complications associated with ulcer like adherent leucoma Amongst infectious keratitis 17 were 7727 of bacterial keratitis and 5 2273 of fungal keratitis Followed by bullous keratopathy 81066 34 of graft rejection and one each 133 of Fuchs dystrophy and chronic actinic keratopathyOf 81 donors corneal tissues 75 were the residual corneal tissues from corneoconjunctival junction which were transplanted within stipulated time Only one case showed changes of chronic actinic keratopathy rest showed normal histology 6 corneas which were not transplanted within stipulated time showed epithelial denudation and stromal degeneration with loss of keratocytesConclusion Histopathology gives additional insight to clinical diagnosis Specific diagnosis can be commented in corneal opacities and infectious keratitisKeywords Penetrating Keratoplasty PK Histopathology Corneal buttons Recipient
Authors and Affiliations
Anupama P. Gupta, Ganesh H. Hake, Dinkar T. Kumbhalkar, A H. Madan
Keywords
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- EP ID EP490572
- DOI 10.18231/2456-9267.2018.0025
- Views 68
- Downloads 0
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