Interface dermatitis-Clinicopathologic Spectrum
Journal Title: IP Archives of Cytology and Histopathology Research - Year 2016, Vol 1, Issue 2
Abstract
Introduction: Interface dermatitis (ID) includes numerous skin dermatoses which have in common salient histopathological features but varied clinical presentation that have traditionally been referred to as the lichenoid tissue reaction/ID. The primary morphologic change is noted at the dermoepidermal junction with secondary susequent changes in the epidermis. The prototypic skin disease in this category is lichen planus (LP) and its variants. Several other inflammatory, infective and neoplastic conditions may show interface change. Aim: The present study was planned to correlate the significance of Interface dermatitis with their clinico-pathological aspects. Methodology: The material for the present retrospective study consisted of skin biopsy samples received from the outpatient department of dermatology. The study was done for a period of six years from 2009 to 2015. Results: In the present study, a total of 54 cases were analysed which clinically presented as papulosquamous disorders. Majority of the cases were seen in women. On histopathological diagnosis majority were LP and its variants. The most consistent histolopathological feature noted was basal cell vacuolar degeneration in the epidermis along with a band of lymphocytic inflammatory infiltrate and pigment incontinence in the dermis. Clinicopathologic concordance was seen in 45 cases (83.33%) and discordance in 8 cases (14.81%). Conclusion: Thus, combination of the histologic details, in correlation with the clinical data helps in arriving at a specific diagnosis of various ID.
Authors and Affiliations
B. G. Malathi, Jasneet Kaur Sandhu
Keywords
Related Articles
- EP ID EP232865
- DOI -
- Views 116
- Downloads 0
Analysis of PAX5 expression of Hodgkin’s and non-Hodgkin’s lymphomas: in comparison with routine panel
Aim of the study: To assess the expression of PAX5 in different types and stages of lymphomas and to study its utility in comparison with the classical pan B and T cell markers. Materials and Methods: Immunohistochemistr...
Interface dermatitis-Clinicopathologic Spectrum
Introduction: Interface dermatitis (ID) includes numerous skin dermatoses which have in common salient histopathological features but varied clinical presentation that have traditionally been referred to as the lichenoid...
Cytological diagnosis of ductal papilloma: an unusual entity in male breast
Cytological interpretation of papillary lesions of the breast remains a challenging task due to its overlapping features of benign, atypical and malignant subtypes. Papillomas of the breast are relatively rare benign les...
A study of cyto-histological correlation in diagnosis of mycetoma cases
Context: Mycetoma is a chronic, specific, granulomatous, progressive subcutaneous disease, characterised by sinuses discharging pus with granules. Actinomycetes and eumycetes are the causative agents. In the absence of d...
Cytomorphological Evaluation of Gouty Tophi- A case report
Soft tissue nodules around joints can pose a diagnostic challenge to clinicians as well as pathologist and radiologist. The periarticular nodules have many differentials from inflammatory to neoplastic ones. Gouty tophi...