CLUSTERING TECHNIQUES FOR DNA MICROARRAY BASED GENE EXPRESSION DATA SURVEY
Journal Title: International Journal of Engineering Sciences & Research Technology - Year 30, Vol 4, Issue 7
Abstract
The advent of DNA microarray technology has enabled biologists to monitor the expression levels (MRNA) of thousands of genes simultaneously. Cluster analysis seeks to partition a given data set into groups based on specified featuresso that the data points within a group are more similar to each other than the points in differentgroups. Many conventional clustering algorithms have been adapted or directly applied to gene expression data, and also new algorithms have recently been proposed specifically aiming at gene expression data. These clustering algorithms have been proven useful for identifying biologicallyrelevant groups of genes and samples.In this survey, the var ious approaches to gene expression data analysis using clustering techniques are addressed. Then the performances of various existing clustering algorithms under each of these approachesare discussed. The specific challenges pertinent toeach clustering category and introduce several representative approaches are presented. And also theproblems of cluster validation are discussed and review various methods to assess the qualityand reliability of clustering results. Finally, this paper is concluded and suggests the promisingtrends in this field.
Authors and Affiliations
K. Sathishkumar
Keywords
Related Articles
- EP ID EP95217
- DOI -
- Views 67
- Downloads 0
Comparative Analysis of Various Condenser in Vapour Compression Refrigeration System
The present work is to analyze performance of refrigeration system on three condensers viz. micro-channel, round tube and coil tube using R134a and R290 refrigerants. These three condensers are kept in parallel wi...
Risk Assessment in Residential Construction Projects by SPSS
Risk management is about thinking ahead and preventing things from going wrong. Managing risks in construction projects have been recognized as a very important process in order to achieve project objectives in t...
PROPOSED SRAM CELL USING LOW POWER SCHMITT TRIGGER IN SUBTHRESHOLD REGION WHICH ADAPTS ITS OWN THRESHOLD
In 1950, an American biophysicist and polymath Otto Schmitt coined the term ‘Biomimetics’ (imitation of nature element, systems, models for the purpose of solving complex problems of the human). Proceeding on the...
REVIEW PAPER ON BROADBAND ANTENNA FOR MODERN WIRELESS COMMUNICATION
In this Review Paper on Broadband - Antenna is presented. There are many researchers who have contributed to the field of broadband antenna techniques in early days. Over the period of time researchers have contri...
GENETIC ALGORITHM BASED AVAILABLE TRANSFER CAPABILITY CALCULATIONS
In the present power market a large number of transmi ssion transactions are required to meet the heavy competition in the electrical industry. These transactions are limited by the system design and operating conditi...