COEXISTENCE OF HASHIMOTO’S THYROIDITIS WITH PAPILLARY CARCINOMA THYROID: A RARE CASE REPORT WITH REVIEW OF LITERATURE
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2014, Vol 3, Issue 3
Abstract
Hashimoto’s thyroiditis is an inflammatory disease of the thyroid gland. It has an autoimmune etiology. A higher incidence of papillary thyroid carcinoma with Hashimoto’s thyroiditis was reported in several studies. 51 year old female patient presented with a swelling in front of the neck region since 5 years. Clinical examination revealed a swelling about 4x4x3 cm, smooth, tender, non-pulsatile and moved with deglutition. Ultrasonography revealed multinodular goiter without evidence of lymphadenpathy. Thyroid profile was done. Patient was euthyroid. FNAC reported as benign lesion. Hemithyroidectomy was done. Grossly thyroidectomy specimen i.e. hemithyroid 6x3x3 cm was received which was externally capsulated and nodular. Cut section showed a greyish white area and cystic areas each of size 1x1 cm filled with haemorrhagic and mucoid material respectively. Microscopy showed thyroid follicles with lymphoid infiltrate in the stroma forming follicles with germinal centres. Hurthle cell change was also noted. Section from both cystic areas showed plenty of complex branching papillae with fibrovascular core lined by cuboidal cells showing ground glass nuclei. The case was diagnosed as papillary carcinoma in Hashimoto’s thyroiditis. The frequency of the association of Hashimoto’s thyroiditis and differentiated thyroid carcinoma is approximately 30%. However, the presence of Hashimoto’s thyroiditis has no effect on the diagnostic evaluation and management of papillary carcinoma of thyroid. Yet, one has to keep an eye for the features of papillary carcinoma in case of Hashimoto’s thyroiditis. So a thorough grossing of thyroid specimen is recommended especially in patients who have Hashimoto’s thyroiditis.
Authors and Affiliations
Mahajan Meera S| Lecturer, Department of Pathology, MGM Medical College and Hospital, N-6 Cidco, Aurangabad, Maharashtra, Corresponding Author email ID: meeramahajan12@gmail.com, Bindu Suparna M| Associate Professor, Department of Pathology, MGM Medical College and Hospital, N-6 Cidco, Aurangabad, Maharashtra, Taksali Reeta N| Lecturer, Department of Pathology, MGM Medical College and Hospital, N-6 Cidco, Aurangabad, Maharashtra, Kale Apurva V| Resident, Department of Pathology, MGM Medical College and Hospital, N-6 Cidco, Aurangabad, Maharashtra, Mulay Smita S| HOD and Professor, Department of Pathology, MGM Medical College and Hospital, N-6 Cidco, Aurangabad, Maharashtra
Keywords
Related Articles
- EP ID EP11235
- DOI 10.5958/2319-5886.2014.00419.6
- Views 307
- Downloads 15
Impact of smoking on aerobic capacity in young adult smokers
Cigarette smoking is a worldwide public health challenge, ,Cigarette smoking is also a strong risk factor for musculoskeletal and cardiovascular disease, It is also well known that low and declining muscle strength is l...
Detection of bacterial pathogens in surgical site infections and their antibiotic sensitivity profile
Surgical site infections considered as a major problem in health care centers, resulting in extended length of stay, substantial associated morbidity and mortality, and high excess hospital cost. Thirty wound swabs were...
To compare the effect of Active Neural Mobilization during Intermittent Lumbar Traction and Intermittent Lumbar Traction followed by Active Neural Mobilization in cases of Lumbar Radiculopathy
To compare the effectiveness of Active neural mobilization (ANM) during intermittent lumbar traction (ILT) and intermittent lumbar traction followed by active neural mobilization treatment in patients of low back pain (...
Effect of Bowen Technique versus Muscle Energy Technique on Asymptomatic Subjects with Hamstring Tightness: A Randomized Clinical Trial
Background: To study and compare the effectiveness of Bowen technique and muscle energy technique in asymptomatic subjects with hamstring tightness. Methods: Forty-eight normal healthy subjects (24 in each group) were r...
IMPACT OF EARLY COLLEGE EDUCATION AMONG POLYTECHNIC STUDENTS
Emotional Quotient (EQ) and Personality plays a vital role in every one’s life and paves way for a successful future. Emotional quotient and Personality assessment were conducted among polytechnic students through qu...