COLLAGEN-ALBUMIN-GENTAMICIN HYDROGELS USABLE FOR INFECTED WOUND HEALING
Journal Title: Revista de Pielărie Încălţăminte - Year 2015, Vol 15, Issue 4
Abstract
The aim of this study was to develop new hydrogels for infected wound treatment. The main components of hydrogels were two proteins, one fibrous (type I collagen in the form of gel) and one globular (albumin) in different ratios (10, 20 and 30%), and gentamicin was selected as an antibiotic drug model. The properties of the obtained hydrogels were estimated by rheological measurements and the corresponding lyophilized forms by water up-take capacity. The results showed that the promising hydrogels which can provide good absorbance and antimicrobial properties at the same time are the ones with maximum 20% albumin and 0.2% gentamicin and the in vitro tests are further recommended.
Authors and Affiliations
Georgeta PĂUNICĂ-PANEA, Mihaela Violeta GHICA, Ştefania MARIN, Ana-Maria ENE, Maria Minodora MARIN, Elena DĂNILĂ, Cornelia NIŢIPIR, Mădălina Georgiana ALBU, Ioan CRISTESCU
Keywords
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