Common carotid intima-media thickness assessment in morbidly obese patients undergoing bariatric surgery
Journal Title: Postępy Nauk Medycznych - Year 2013, Vol 26, Issue 4
Abstract
<b>Introduction.</b> Obesity is a pathological accumulation of adipose tissue in the organism, and leads to the development of diseases, including cardiovascular diseases.<br><b>Aim.</b> The aim of the study was to assess common carotid artery intima-media thickness in morbidly obese patients as well as to study the influence of bariatric surgery on studied parameter.<br><b>Material and methods.</b> In all 40 patients we performed: anthropometric, basic laboratory measurement and common carotid artery intima-media thickness, (IMT), (Philips iE 33 system: Andeouver, Massachusetts USA). The protocol was approved by Warsaw Medical University’s Bioethics Committee.<br><b>Results. </b>Body mass of patients diagnosed with severe obesity changed during the 6-month follow-up post-surgery period (132.03 ± 18.42 vs. 97.46 ± 15.35 kg; p < 0.0001). Fat mass decreased similarly: 49.15 ± 3.83% (OB1) vs. 38.20 ± 5.66% (OB2); (p < 0.0001). Intima-media thickness varied statistically between both groups (OB1, OB2) (0.59 ± 0.11 vs. 0.52 ± 0.011 mm; p < 0.0001), and were within the reference value range (IMT < 0.9 mm). In the control group IMT values were lower than in OB1 (0.59 ± 0.11 vs. 0.42 ± 0.026 mm; p = 0.0001). In OB1 IMT correlated with body mass (r = 0.472; p = 0.002), free fatty mass (r = 0.427, p = 0.0059), fatty mass (r = 0.368, p = 0.019), BMI (r = 0.423; p = 0.006), HbA<sub>1</sub>C (r = 0.296; p = 0.063).<br><b>Conclusions.</b> Noninvasive assessment of common carotid artery IMT showed unfavorable change in the group of morbidly obese patients in comparison to healthy persons. Weight reduction as a result of bariatric surgery leads to the decrease in IMT as well as beneficial metabolic changes.
Authors and Affiliations
Justyna Domienik-Karłowicz, Olga Dzikowska-Diduch, Wojciech Lisik, Andrzej Chmura, Piotr Pruszczyk
Keywords
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