COMMON INFECTING BACTERIA AND ANTIBIOTIC SENSITIVITY PATTERN IN PATIENTS WITH SEVERE LOWER RESPIRATORY TRACT INFECTIONS AT A TERTIARY CARE HOSPITAL
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 73
Abstract
BACKGROUND Lower respiratory tract infections are the commonest infectious diseases affecting humans worldwide. They are considered a major public health problem and cause morbidity and mortality. Acute and chronic bronchitis, influenza, pneumonia, lung abscess and infective exacerbations of bronchiectasis are the common lower respiratory infections that present at tertiary care hospitals. In this study, we are considering pneumonia, lung abscess and infective exacerbations of bronchiectasis as they are of bacterial origin and culture and sensitivity and isolation is easier at our institute, viral assays are not available. This study was started to understand the common bacteria isolated in patients with severe lower respiratory tract infections and the antibiotic sensitivity pattern in these patients. MATERIALS AND METHODS All patients with severe lower respiratory tract infections – Pneumonia, Lung abscess and Bronchiectasis who presented to Chest OP and Emergency Department of SVRR Government General Hospital, Tirupati, Andhra Pradesh were recruited to the study. Diagnosis was made by detailed history taking, Chest x-ray, CT scan of chest where necessary, Sputum Gram Staining and Pyogenic culture. Empirical antibiotics were started and later antibiotics were changed based on susceptibility pattern. RESULTS Out of 100 patients recruited to the study, 64 were male and 36 were female. Pneumonia was seen in 58 patients, Bronchiectasis in 32 patients, Lung abscess in 10 patients. Most common organisms isolated were Klebsiella, Pneumococci, Staphylococcus aureus, H. Influenza, E. coli, Pseudomonas, M. catarrhalis in that order. Commonest comorbidity was Diabetes (38 cases). Pneumonia patients with 9.8 days admission had the shortest hospital stay. All patients recovered and there were no deaths. CONCLUSION Male patients (64%) are more prone for Serious LRTI due to Alcoholism and smoking and are commonly infected with Klebsiella and Pneumococci. Female patients (36%) are infected more commonly with H. Influenza, Klebsiella and E. coli and showed higher incidence of anaemia and Diabetes. Pneumonia when managed meticulously has a very good prognosis.
Authors and Affiliations
Ramya Sudha Chittoor, Lokeswara Reddy Avula, Aruna Gorthi
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