Comparative Analysis of Autonomic Function Tests in Normotensive Premenopausal and Postmenopausal Women
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 1
Abstract
Aims: The aim of this study was to assess the physiological changes in the autonomic function tests in post-menopausal women. Materials & Methods: 70 normal females (30 premenopausal and 40 post-menopausal) were included in the study. The parasympathetic function tests included pulse rate, heart rate response, heart rate variability, E:I ratio, 30:15 ratio and the valsalva ratio whereas the sympathetic function tests included systolic and diastolic blood pressure, orthostatic tolerance test, isometric handgrip (IHG) test and cold pressor test. Results: HRV, EI ratio, IHG, cold pressor SBP and cold pressor DBP were significantly lower whereas HRR, VR, SBP, DBP, OTT significantly higher in postmenopausal women (p<0.05). When the autonomic function parameters were compared among non-obese and obese post-menopausal women, we found that functions like HRV, VR, EI ratio, IHG, cold pressor SBP were significantly lower whereas functions like HRR, DBP, OTT were significantly higher in the obese post-menopausal women in comparison to non-obese postmenopausal females (p<0.05). BMI was correlated positively with PR, HRR, SBP, DBP, OTT, cold pressor SBP and cold pressor DBP and negatively with HRV, VR, EI, 30:15 and IHG, all of which were statistically significant (p < 0.05). In case of WHR (Waist Hip Ratio), we found significant correlation with HRR, DBP and OTT (p<0.05) and significant negative correlation with HRV, VR, EI, 30:15, and IHG (p<0.05). Conclusion: Obesity, physical inactivity, and altered estrogen metabolism contribute to the risk of diseases in the postmenopausal women. Early and regular screening of obese individuals is necessary to prevent any future complications.
Authors and Affiliations
Uppalapadu Sudarsana, Shailaza Shrestha, Praveen Kumar
Keywords
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- EP ID EP542731
- DOI 10.21276/ijmrp.2017.3.1.047
- Views 82
- Downloads 0
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