Comparative Analysis of Efficacy of Amoxicillin Plain and Amoxicillin with Clavulanate Acid for Odontogenic Space Infections
Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2017, Vol 5, Issue 12
Abstract
Background: The treatment of odontogenic infections is based on two main elements: surgical treatment and antibiotic therapy. In most cases antibiotic prescription is empirical and relates to a number of factors that are not always well known and defined, and among which are included the perception efficacy, the knowledge of empirical therapy recommendations, opinions regarding the most common etiology, the expected bacterial resistance as well as knowing the existence of different antibiotics. Aim of study: To compare the efficacy of amoxicillin plain and amoxicillin with clavulanate acid for odontogenic space infections. Materials and methods: The study was conducted in the department of oral surgery of the dental institution. We selected 50 patients with space infections from the outpatient clinic of the department. The patients were randomly divided into two groups, Group A and B with 25 patients in each group. The patients in Group A were prescribed Amoxycillin 500 mg for 7 days and patients in Group 2 were prescribed Amoxycillin and Clavulante acid 625 mg for 7 days. After completion of 7 days patients were recalled to the department and clinical symptoms were assessed. Results: Number of male patients was 31 and number of female patients was 19. The mean age of the subjects was 42.23 + 2.1 years ranging from 21 to 65 years. Number of patients with Score 0 was 18 in Group A and 11 in Group B. Number of patients with Score 1 was 5 in Group A and 8 in Group B. Number of patients with Score 2 was 2 in Group A and 4 in Group B. Number of patients with Score 3 was 0 in Group A and 2 in Group B. Number of patients with Score 4 was 0 in both the groups. On comparing the results we observed statistically non-significant results. Conclusion: Within the limitations of the present study, we conclude that amoxicillin plain and amoxicillin with clavulanate acid can be prescribed for space infections for positive results.
Authors and Affiliations
Varun Salgotra, Sanjay Kumar Bhagat, Syed Wakeel
Keywords
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