COMPARATIVE ANTIBACTERIAL ACTIVITIES OF THE COMBINED CRUDE LEAF EXTRACT OF BIXA ORELLANA, AZADIRACHTA INDICA AND OCIMUM SCANTUM
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2013, Vol 4, Issue 4
Abstract
In the present paper, we analyze the past, present and future of medicinal plants, both as potential antimicrobial crude drugs as well as a source for natural compounds that act as new anti-infection agents. Ethanol extracts of the leaves of Bixa orellana, Azadirachta indica & Ocimum scantum were investigated for their invitro antimicrobial properties. Fresh leaves were collected randomly from Bhimavaram region, India. Plants were compared with voucher specimens deposited by Dr. B. Sarveswara Lingam at Department of Botany, K.G.R.L College (Autonomous), Bhimavaram, Andhra Pradesh, India. The aim of study was to scientifically test whether plant used in traditional medicine for the treatment of infection showed antibacterial activity. Extracts of sample of 3 species traditionally used as antibacterial were screened for activity against Esherichia coli, Pseudomonas aeruginosa & Staphylococcus aurues. The study confirms that simple laboratory methods are very well suited to assess the efficacy of traditionally used medicinal plants to inhibit bacterial growth. A comparison to the traditional uses also indicate that local knowledge can give important leads for the development of new treatments. Further tests, especially with regards to toxicity, are needed to verify the safety of the traditional preparations.
Authors and Affiliations
B. UttamKumar, A. Bhubaneswari, M. V. V Tejasri, P. Radhakrishna, K. D , K. Amrita
Keywords
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- EP ID EP93309
- DOI 10.7897/2230-8407.04437
- Views 112
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