Comparative Assessment of Effect of Phytoestrogen and Conjugated Oestrogen on Vasomotor Symptoms in Surgical Menopause
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 5
Abstract
Background: The reproductive life span of women is 36 years. Menopause is defined as permanent stoppage of menses. During the phase women goes through various mental, psychological and physical changes. Various plant derived substances which are structurally similar to oestrogen and bind to oestrogen receptors, also known as phytoestrogens are used for relief of vasomotor symptoms. The present study was conducted to compare the effect of phytoestrogen and conjugated oestrogen on vasomotor symptoms. Materials and Methods: The present study was conducted in the Department of Obstetrics and Gynaecology, OPD of Govt. Medical College and Rajindra Hospital Patiala during a period of one year. It was conducted from June 2016 to June 2017. A detailed medical and gynaecological history was obtained from all the patients. Vasomotor symptoms like hot flushes and night sweats were noted. All the symptoms were noted on a four point scale with 0 means none and 3 indicating severe symptoms. Patients were divided into group-I and group-II. Patients were followed up for a period of 3 months and the symptoms were recorded again after giving phytoestrogen to group-I and conjugated oestrogen to group-II .Chi square test was used to compare the results. Probability value less than 0.05 was considered significant. Results: In group I the mean age of women was 51.6±5.2 years and in group II, the mean age of women was 49.8±4.7 years. The mean height in Group I and group II was 153.9±6.3 cm and 151.4±4.7 cm respectively. The baseline score recorded in group I was 0.48±0.81 and in group II was 0.51±0.76. There was a mean change of 0.03±0.08 and 0.04±0.08 in group I and group II respectively. There was no significant change in vasomotor symptoms amongst both the groups (p>0.05). Conclusion: From the present study we concluded that phytoestrogens are a safe and effective alternative to conjugated estrogens but still there is lack of information about the exact dosage and the long term side effects associated with its use.
Authors and Affiliations
Gurdip Kaur, Harcharan Singh
Keywords
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- EP ID EP547303
- DOI 10.21276/ijmrp.2017.3.5.008
- Views 49
- Downloads 0
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