COMPARATIVE EVALUATION OF BUTORPHANOL AND FENTANYL FOR EPIDURAL ANALGESIA IN LOWER LIMB SURGERIES
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 15
Abstract
BACKGROUND Epidural and spinal blocks are major regional techniques with a long history of effective use for a variety of surgical procedures and pain relief. Epidural block with the catheter technique gives a better control of the level of analgesia and can be used for providing post-operative pain relief by opioids or local anaesthetic agents. The purpose of the present study was to compare the safety and efficacy of epidural butorphanol versus epidural fentanyl as adjuvants to bupivacaine for lower limb surgeries. MATERIALS AND METHODS 100 patients were randomised into two groups with 50 patients in each group: Group BB- epidural administration of 20 mL 0.5% plain bupivacaine with [1 mg (1 mL) butorphanol + 1 mL NS= 2 mL]. Group BF- epidural administration of 20 mL 0.5% plain bupivacaine with 100 mcg (2 mL) of fentanyl. Settings and Design- Randomised double-blind trial. RESULTS The mean onset of sensory blockade and time for maximum sensory blockade was observed to be significantly reduced with the addition of fentanyl to bupivacaine as compared to butorphanol and bupivacaine. The results showed statistically significant increase in the duration of analgesia with the addition of fentanyl to bupivacaine as compared to butorphanol and bupivacaine. CONCLUSION We can conclude that butorphanol and fentanyl were effective adjuvants to bupivacaine when used epidurally in patients undergoing lower limb surgery. Although, epidural fentanyl with bupivacaine produces significantly faster onset of sensory blockade compared to epidural butorphanol; however, epidural butorphanol with bupivacaine produces significantly prolonged duration of analgesia compared to epidural fentanyl.
Authors and Affiliations
Tejinderpal Kaur Grewal, Simrit Kaur, Balwinder Kaur, Parmod Kumar, Sandeep Kaur Sidhu
Keywords
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- EP ID EP414416
- DOI 10.14260/jemds/2018/417
- Views 87
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