Comparative Evaluation of Efficacy of Intrathecal Isobaric Ropivacaine 0.75% Versus Isobaric Ropivacaine 0.75% with Dexmedetomidine for Infraumbilical Surgeries

Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 3

Abstract

Background: Various adjuvants are being used for spinal anaesthesia. Dexmedetomidine hydrochloride is a newer alpha2 agonist with sedative, analgesic and anxiolytic properties. Ours was a comparative study of efficacy of intrathecal isobaric Ropivacaine 0.75% plain with adjuvant Dexmedetomidine for elective infraumbilical surgeries. Materials & Methods: Prospective randomized study (May 2011- May 2013) on 60 patients of ASA 1-2, 18-60 years of either sex, 40-80kg with a random allocation to Group R (3.5 ml 0.75% isobaric Ropivacaine) and Group D (3.0 ml 0.75% isobaric Ropivacaine + 10 micrograms (0.1ml) Dexmedetomidine + 0.4 ml NS. Total volume 3.5 ml) was done. Results: Group D patients had reduced dose, faster onset, significantly longer and effective sensory and motor blockade, hemodynamic stability, reduced demand of post-operative analgesics (P value < 0.05). Conclusion: Addition of 10 micrograms Dexmedetomidine to intrathecal isobaric Ropivacaine 0.75% enhances sensory and motor blockade, offers hemodynamic stability and reduces demand of postoperative analgesics.

Authors and Affiliations

Arati Jadhav, Smit Kadakia, I. J. Namazi

Keywords

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  • EP ID EP547777
  • DOI 10.21276/ijmrp.2017.3.3.008
  • Views 95
  • Downloads 0

How To Cite

Arati Jadhav, Smit Kadakia, I. J. Namazi (2017). Comparative Evaluation of Efficacy of Intrathecal Isobaric Ropivacaine 0.75% Versus Isobaric Ropivacaine 0.75% with Dexmedetomidine for Infraumbilical Surgeries. International Journal of Medical Research Professionals, 3(3), 33-37. https://europub.co.uk/articles/-A-547777