The Pattern of Histopathology of Gall Bladder of Patients Undergoing Cholecystectomy
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 3
Abstract
Background: Cholecystitis accounts for high mortality and morbidity, with most appropriate treatment being surgical removal of the gallbladder. There seems to be specific need for histopathology of gall bladder, as selective approach for sending cholecystectomy specimens for histopathology can result in missing discrete pathologies such as premalignant lesions like porcelain gallbladder, carcinoma-in-situ, and early carcinomas. Hence it is appropriate to study the pattern of histopathology of gall bladder in patients undergoing cholecystectomy. Methodology: Present study was conducted in Department of Surgery and Pathology, with all patients undergoing open or laparoscopic cholecystectomy. The pattern of response in the gall bladder mucosa was studied. Three sections including neck, body and fundus of gall bladder specimen were obtained. Results: Forty seven patients with symptomatic gallstones were admitted with a female to male ratio of 3:1. The age ranged from 21 to 80 years with a mean age of 45 ± 5 years, most of the patients were in the age group of 51-60 years. The most common findings were of chronic cholecystitis (70.2%), followed by chronic follicular cholecystitis (12.7%). All samples collected showed congestion, whereas edema was found in 46 samples and ulceration was found in 45 samples. Conclusion: To conclude, our study showed that females were more effected from cholecystitis and underwent cholecystectomy. The most common histopathological finding in our study was of chronic cholecystitis followed by chronic follicular cholecystitis. There were no signs or symptoms suggestive or underlying malignancy in any patient.
Authors and Affiliations
Ruchir Taneja, Ashutosh Kumar, Debranjan Datta, Prithpal S Matreja, Shyamoli Dutta
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